Bioactive Inks Development for Osteochondral Tissue Engineering: A Mini-Review
Bakhtiary N, Liu C, Ghorbani F (2021)
Publication Type: Journal article
Publication year: 2021
Journal
Book Volume: 7
Journal Issue: 4
DOI: 10.3390/gels7040274
Abstract
Nowadays, a prevalent joint disease affecting both cartilage and subchondral bone is osteoarthritis. Osteochondral tissue, a complex tissue unit, exhibited limited self-renewal potential. Furthermore, its gradient properties, including mechanical property, bio-compositions, and cellular behaviors, present a challenge in repairing and regenerating damaged osteochondral tissues. Here, tissue engineering and translational medicine development using bioprinting technology provided a promising strategy for osteochondral tissue repair. In this regard, personalized stratified scaffolds, which play an influential role in osteochondral regeneration, can provide potential treatment options in early-stage osteoarthritis to delay or avoid the use of joint replacements. Accordingly, bioactive scaffolds with possible integration with surrounding tissue and controlling inflammatory responses have promising future tissue engineering perspectives. This minireview focuses on introducing biologically active inks for bioprinting the hierarchical scaffolds, containing growth factors and bioactive materials for 3D printing of regenerative osteochondral substitutes.
Authors with CRIS profile
Involved external institutions
Tarbiat Modares University
Iran, Islamic Republic of (IR)
University College London (UCL)
United Kingdom (GB)
Iran, Islamic Republic of (IR)
University College London (UCL)
United Kingdom (GB)
How to cite
APA:
Bakhtiary, N., Liu, C., & Ghorbani, F. (2021). Bioactive Inks Development for Osteochondral Tissue Engineering: A Mini-Review. Gels, 7(4). https://dx.doi.org/10.3390/gels7040274
MLA:
Bakhtiary, Negar, Chaozong Liu, and Farnaz Ghorbani. "Bioactive Inks Development for Osteochondral Tissue Engineering: A Mini-Review." Gels 7.4 (2021).
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