Improving Generalization Capability of Multiorgan Segmentation Models Using Dual-Energy CT

Chen S, Zhong X, Dorn S, Ravikumar N, Tao Q, Huang X, Lell M, Kachelriess M, Maier A (2022)

Publication Type: Journal article

Publication year: 2022

Journal

Book Volume: 6

Pages Range: 79-86

Journal Issue: 1

DOI: 10.1109/TRPMS.2021.3055199

Abstract

Multiorgan segmentation in computed tomography (CT) images is essential for a variety of clinical applications. Due to variations in acquisition protocols, clinical data differ in terms of soft-tissue contrast, noise, and artifacts. Devising automatic multiorgan segmentation approaches, which are generalized to data acquired using different CT protocols, are challenging and essential when conducting any multicenter/scanner analyses. In this study, we investigate the use of dual-energy CT (DECT) images to train a fully convolutional segmentation network which is generalized to CT images acquired using different protocols (i.e., at different energy levels and using a variety of reconstruction kernels) from different CT scanners. Furthermore, a novel image fusion approach in the frequency domain is proposed and compared to state-of-the-art fusion approaches, in terms of the segmentation quality achieved by the network. Overall, the experiments indicate that the generalization capability of the segmentation network is improved using DECT image fusion. The proposed fusion method outperforms all single-energy CT approaches. It provided a significant improvement in segmentation accuracy, ranging from 16.0% to 23.35% with p \leq 0.03. Furthermore, two image fusion methods statistically significantly improve segmentation quality in the abdominal organs compared to simply using all available DECT data.

Authors with CRIS profile

Involved external institutions

Shanghai Jiao Tong University / 上海交通大学 China (CN) Deutsches Krebsforschungszentrum (DKFZ) Germany (DE)

How to cite

APA:

Chen, S., Zhong, X., Dorn, S., Ravikumar, N., Tao, Q., Huang, X.,... Maier, A. (2022). Improving Generalization Capability of Multiorgan Segmentation Models Using Dual-Energy CT. IEEE Transactions on Radiation and Plasma Medical Sciences, 6(1), 79-86. https://dx.doi.org/10.1109/TRPMS.2021.3055199

MLA:

Chen, Shuqing, et al. "Improving Generalization Capability of Multiorgan Segmentation Models Using Dual-Energy CT." IEEE Transactions on Radiation and Plasma Medical Sciences 6.1 (2022): 79-86.

BibTeX: Download