Nanocomposite electrospun fibers of poly(ε-caprolactone)/bioactive glass with shape memory properties
Liverani L, Liguori A, Zezza P, Gualandi C, Toselli M, Boccaccini AR, Focarete ML (2022)
Publication Type: Journal article
Publication year: 2022
Journal
Book Volume: 11
Pages Range: 230-239
DOI: 10.1016/j.bioactmat.2021.09.020
Abstract
Electrospun fibers of shape memory triethoxysilane-terminated poly(epsilon-caprolactone) (PCL-TES) loaded with bioactive glasses (BG) are here presented. Unloaded PCL-TES, as well as PCL/BG nanocomposite fibers, are also considered for comparison. It is proposed that hydrolysis and condensation reactions take place between triethoxysilane groups of the polymer and the silanol groups at the BG particle surface, thus generating additional crosslinking points with respect to those present in the PCL-TES system. The as-spun PCL-TES/BG fibers display excellent shape memory properties, in terms of shape fixity and shape recovery ratios, without the need of a thermal crosslinking treatment. BG particles confer in vitro bioactivity to PCL-based nanocomposite fibers and favor the precipitation of hydroxycarbonate apatite on the fiber surface. Preliminary cytocompatibility tests demonstrate that the addition of BG particles to PCL-based polymer does not inhibit ST-2 cell viability. This novel approach of using bioactive glasses not only for their biological properties, but also for the enhancement of shape memory properties of PCL-based polymers, widens the versatility and suitability of the obtained composite fibers for a huge portfolio of biomedical applications.
Authors with CRIS profile
Liliana Liverani
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Aldo Boccaccini
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Involved external institutions
Italy (IT)How to cite
APA:
Liverani, L., Liguori, A., Zezza, P., Gualandi, C., Toselli, M., Boccaccini, A.R., & Focarete, M.L. (2022). Nanocomposite electrospun fibers of poly(ε-caprolactone)/bioactive glass with shape memory properties. Bioactive Materials, 11, 230-239. https://dx.doi.org/10.1016/j.bioactmat.2021.09.020
MLA:
Liverani, Liliana, et al. "Nanocomposite electrospun fibers of poly(ε-caprolactone)/bioactive glass with shape memory properties." Bioactive Materials 11 (2022): 230-239.
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