Dye-functionalized phosphate-binding macrocycles: from nucleotide to G-quadruplex recognition and "turn-on" fluorescence sensing

Oshchepkov A, Reznichenko O, Xu D, Morozov B, Granzhan A, Kataev E (2021)

Publication Type: Journal article

Publication year: 2021

Journal

Chemical Communications Royal Society of Chemistry

DOI: 10.1039/d1cc04096k

Abstract

A novel strategy to design "turn-on" fluorescent receptors for G-quadruplexes of DNA is presented, which relies on the connection of phosphate binding macrocycles (PBM) with naphthalimide dyes. A new PBM-dye family was synthesized and evaluated in terms of binding and detection of nucleotides and DNA G-quadruplexes of different topologies.

Authors with CRIS profile

Aleksandr Oshchepkov Lehrstuhl für Organische Chemie II Boris Morozov Lehrstuhl für Organische Chemie II Evgeny Kataev Lehrstuhl für Organische Chemie II

Involved external institutions

École Polytechnique - Université Paris-Saclay FR France (FR) Technische Universität Chemnitz DE Germany (DE)

How to cite

APA:

Oshchepkov, A., Reznichenko, O., Xu, D., Morozov, B., Granzhan, A., & Kataev, E. (2021). Dye-functionalized phosphate-binding macrocycles: from nucleotide to G-quadruplex recognition and "turn-on" fluorescence sensing. Chemical Communications. https://dx.doi.org/10.1039/d1cc04096k

MLA:

Oshchepkov, Aleksandr, et al. "Dye-functionalized phosphate-binding macrocycles: from nucleotide to G-quadruplex recognition and "turn-on" fluorescence sensing." Chemical Communications (2021).

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