Breath biomarkers in diagnostic applications
Pham YL, Beauchamp J (2021)
Publication Type: Journal article, Review article
Publication year: 2021
Journal
Book Volume: 26
Article Number: 5514
Journal Issue: 18
DOI: 10.3390/molecules26185514
Abstract
The detection of chemical compounds in exhaled human breath presents an opportunity to determine physiological state, diagnose disease or assess environmental exposure. Recent ad-vancements in metabolomics research have led to improved capabilities to explore human metabolic profiles in breath. Despite some notable challenges in sampling and analysis, exhaled breath repre-sents a desirable medium for metabolomics applications, foremost due to its non-invasive, convenient and practically limitless availability. Several breath-based tests that target either endogenous or exogenous gas-phase compounds are currently established and are in practical and/or clinical use. This review outlines the concept of breath analysis in the context of these unique tests and their applications. The respective breath biomarkers targeted in each test are discussed in relation to their physiological production in the human body and the development and implementation of the associated tests. The paper concludes with a brief insight into prospective tests and an outlook of the future direction of breath research.
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Germany (DE)How to cite
APA:
Pham, Y.L., & Beauchamp, J. (2021). Breath biomarkers in diagnostic applications. Molecules, 26(18). https://dx.doi.org/10.3390/molecules26185514
MLA:
Pham, Y Lan, and Jonathan Beauchamp. "Breath biomarkers in diagnostic applications." Molecules 26.18 (2021).
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