7 Tesla Chlorine (Cl-35) and Sodium (Na-23) MR Imaging of an Enchondroma

Weber MA, Seyler L, Nagel AM (2021)


Publication Type: Journal article

Publication year: 2021

Journal

DOI: 10.1055/a-1472-6730

Abstract

We demonstrated the feasibility of 7 Tesla sodium (Na-23) and chlorine (Cl-35) MRI of a solitary enchondroma. For this, we established dedicated sequences on a 7-Tesla whole-body system with the following key parameters for Cl-35 MRI: TE/TR = 0.35/60 ms, T-RO = 5 ms, alpha = 90 degrees, Delta x (3) = (6 mm) (3) , 3 averages, T (acq) = 30 min and for (23) Na MRI: TE/TR = 0.4/101 ms, T (RO) = 10ms; alpha = 90 degrees; Delta x (3) = (1.9 mm) (3) , 3 averages, T (acq) = 30 min 18 s. The measured apparent Na (+) concentration was 255 mmol/l and was approximately 7-fold higher than the apparent Cl (-) concentration with about 36 mmol/l. Additionally, repeated proton MRI examinations demonstrated constant but subtle growth (approximate to 0.65 ml/year) over 14 years. In conclusion, enchondromas obviously have a high contrast-to-noise ratio when compared with the normal bone marrow in (23) Na and (35) Cl MRI, which may contribute to detection and differentiation in unclear or subtle cases.

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APA:

Weber, M.-A., Seyler, L., & Nagel, A.M. (2021). 7 Tesla Chlorine (Cl-35) and Sodium (Na-23) MR Imaging of an Enchondroma. Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. https://dx.doi.org/10.1055/a-1472-6730

MLA:

Weber, Marc-Andre, Lisa Seyler, and Armin Michael Nagel. "7 Tesla Chlorine (Cl-35) and Sodium (Na-23) MR Imaging of an Enchondroma." Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren (2021).

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