Interactive Volumetry of Liver Ablation Zones

Egger J, Busse H, Brandmaier P, Seider D, Gawlitza M, Strocka S, Voglreiter P, Dokter M, Hofmann M, Kainz B, Hann A, Chen X, Alhonnoro T, Pollari M, Schmalstieg D, Moche M (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Scientific Reports Nature Publishing Group: Open Access Journals - Option B

Book Volume: 5

Article Number: 15373

DOI: 10.1038/srep15373

Abstract

Percutaneous radiofrequency ablation (RFA) is a minimally invasive technique that destroys cancer cells by heat. The heat results from focusing energy in the radiofrequency spectrum through a needle. Amongst others, this can enable the treatment of patients who are not eligible for an open surgery. However, the possibility of recurrent liver cancer due to incomplete ablation of the tumor makes post-interventional monitoring via regular follow-up scans mandatory. These scans have to be carefully inspected for any conspicuousness. Within this study, the RF ablation zones from twelve post-interventional CT acquisitions have been segmented semi-automatically to support the visual inspection. An interactive, graph-based contouring approach, which prefers spherically shaped regions, has been applied. For the quantitative and qualitative analysis of the algorithm's results, manual slice-by-slice segmentations produced by clinical experts have been used as the gold standard (which have also been compared among each other). As evaluation metric for the statistical validation, the Dice Similarity Coefficient (DSC) has been calculated. The results show that the proposed tool provides lesion segmentation with sufficient accuracy much faster than manual segmentation. The visual feedback and interactivity make the proposed tool well suitable for the clinical workflow.

Authors with CRIS profile

Bernhard Kainz

Involved external institutions

Aalto University Espoo FI Finland (FI) Universitätsklinikum Leipzig DE Germany (DE) Technische Universität Graz AT Austria (AT) Katharinenhospital Stuttgart DE Germany (DE) Shanghai Jiao Tong University / 上海交通大学 CN China (CN) Imperial College London / The Imperial College of Science, Technology and Medicine GB United Kingdom (GB)

How to cite

APA:

Egger, J., Busse, H., Brandmaier, P., Seider, D., Gawlitza, M., Strocka, S.,... Moche, M. (2015). Interactive Volumetry of Liver Ablation Zones. Scientific Reports, 5. https://dx.doi.org/10.1038/srep15373

MLA:

Egger, Jan, et al. "Interactive Volumetry of Liver Ablation Zones." Scientific Reports 5 (2015).

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