IQ67 DOMAIN proteins facilitate preprophase band formation and division-plane orientation
Kumari P, Dahiya P, Livanos P, Zergiebel L, Koelling M, Poeschl Y, Stamm G, Hermann A, Abel S, Buerstenbinder K, Müller S (2021)
Publication Type: Journal article
Publication year: 2021
Journal
Book Volume: 7
Pages Range: 739-747
Journal Issue: 6
DOI: 10.1038/s41477-021-00923-z
Abstract
Spatiotemporal control of cell division is essential for the growth and development of multicellular organisms. In plant cells, proper cell plate insertion during cytokinesis relies on the premitotic establishment of the division plane at the cell cortex. Two plant-specific cytoskeleton arrays, the preprophase band (PPB) and the phragmoplast, play important roles in division-plane orientation and cell plate formation, respectively1. Microtubule organization and dynamics and their communication with membranes at the cortex and cell plate are coordinated by multiple, mostly distinct microtubule-associated proteins2. How division-plane selection and establishment are linked, however, is still unknown. Here, we report members of the Arabidopsis IQ67 DOMAIN (IQD) family3 as microtubule-targeted proteins that localize to the PPB and phragmoplast and additionally reside at the cell plate and a polarized cortical region including the cortical division zone (CDZ). IQDs physically interact with PHRAGMOPLAST ORIENTING KINESIN (POK) proteins4,5 and PLECKSTRIN HOMOLOGY GTPase ACTIVATING (PHGAP) proteins6, which are core components of the CDZ1. The loss of IQD function impairs PPB formation and affects CDZ recruitment of POKs and PHGAPs, resulting in division-plane positioning defects. We propose that IQDs act as cellular scaffolds that facilitate PPB formation and CDZ set-up during symmetric cell division.
Authors with CRIS profile
Involved external institutions
Leibniz Institute of Plant Biochemistry / Leibniz-Institut für Pflanzenbiochemie
Germany (DE)
Eberhard Karls Universität Tübingen
Germany (DE)
Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv)
Germany (DE)
Germany (DE)
Eberhard Karls Universität Tübingen
Germany (DE)
Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv)
Germany (DE)
How to cite
APA:
Kumari, P., Dahiya, P., Livanos, P., Zergiebel, L., Koelling, M., Poeschl, Y.,... Müller, S. (2021). IQ67 DOMAIN proteins facilitate preprophase band formation and division-plane orientation. Nature Plants, 7(6), 739-747. https://doi.org/10.1038/s41477-021-00923-z
MLA:
Kumari, Pratibha, et al. "IQ67 DOMAIN proteins facilitate preprophase band formation and division-plane orientation." Nature Plants 7.6 (2021): 739-747.
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