Germanium Plasmon Enhanced Resonators for Label-Free Terahertz Protein Sensing

Bettenhausen M, Roemer F, Witzigmann B, Flesch J, Kurre R, Korneev S, Piehler J, You C, Kazmierczak M, Guha S, Capellini G, Schroeder T (2018)


Publication Type: Journal article

Publication year: 2018

Journal

Book Volume: 72

Pages Range: 113-122

Journal Issue: 3-4

DOI: 10.1515/freq-2018-0009

Abstract

A Terahertz protein sensing concept based on subwavelength Ge resonators is presented. Ge bowtie resonators, compatible with CMOS fabrication technology, have been designed and characterized with a resonance frequency of 0.5 THz and calculated local intensity enhancement of 10.000. Selective biofunctionalization of Ge resonators on Si wafer was achieved in one step using lipoic acid-HaloTag ligand (LA-HTL) for biofunctionalization and passivation. The results lay the foundation for future investigation of protein tertiary structure and the dynamics of protein hydration shell in response to protein conformation changes.

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APA:

Bettenhausen, M., Roemer, F., Witzigmann, B., Flesch, J., Kurre, R., Korneev, S.,... Schroeder, T. (2018). Germanium Plasmon Enhanced Resonators for Label-Free Terahertz Protein Sensing. Frequenz, 72(3-4), 113-122. https://dx.doi.org/10.1515/freq-2018-0009

MLA:

Bettenhausen, Maximilian, et al. "Germanium Plasmon Enhanced Resonators for Label-Free Terahertz Protein Sensing." Frequenz 72.3-4 (2018): 113-122.

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