Müller T, Gollwitzer S, Hopfengartner R, Rampp S, Lang J, Stritzelberger J, Madzar D, Reindl C, Sprügel M, Onugoren MD, Mühlen I, Kuramatsu J, Schwab S, Huttner H, Hamer H (2021)
Publication Type: Journal article
Publication year: 2021
Book Volume: 132
Pages Range: 1283-1289
Journal Issue: 6
DOI: 10.1016/j.clinph.2021.03.005
Objective: In subarachnoid hemorrhage (SAH), transcranial Doppler/color-coded-duplex sonography (TCD/TCCS) is used to detect delayed cerebral ischemia (DCI). In previous studies, quantitative electroencephalography (qEEG) also predicted imminent DCI. This study aimed to compare and analyse the ability of qEEG and TCD/TCCS to early identify patients who will develop later manifest cerebral infarction. Methods: We analysed cohorts of two previous qEEG studies. Continuous six-channel-EEG with artefact rejection and a detrending procedure was applied. Alpha power decline of ≥ 40% for ≥ 5 hours compared to a 6-hour-baseline was defined as significant EEG event. Median reduction and duration of alpha power decrease in each channel was determined. Vasospasm was diagnosed by TCD/TCCS, identifying the maximum frequency and days of vasospasm in each territory. Results: 34 patients were included (17 male, mean age 56 ± 11 years, Hunt and Hess grade: I–V, cerebral infarction: 9). Maximum frequencies in TCD/TCCS and alpha power reduction in qEEG were correlated (r = 0.43; p = 0.015). Patients with and without infarction significantly differed in qEEG parameters (maximum alpha power decrease: 78% vs 64%, p = 0.019; summed hours of alpha power decline: 236 hours vs 39 hours, p = 0.006) but showed no significant differences in TCD/TCCS parameters. Conclusions: There was a moderate correlation of TCD/TCCS frequencies and qEEG alpha power reduction but only qEEG differentiated between patients with and without cerebral infarction. Significance: qEEG represents a non-invasive, continuous tool to identify patients at risk of cerebral infarction.
APA:
Müller, T., Gollwitzer, S., Hopfengartner, R., Rampp, S., Lang, J., Stritzelberger, J.,... Hamer, H. (2021). Alpha power decrease in quantitative EEG detects development of cerebral infarction after subarachnoid hemorrhage early. Clinical Neurophysiology, 132(6), 1283-1289. https://dx.doi.org/10.1016/j.clinph.2021.03.005
MLA:
Müller, Tamara, et al. "Alpha power decrease in quantitative EEG detects development of cerebral infarction after subarachnoid hemorrhage early." Clinical Neurophysiology 132.6 (2021): 1283-1289.
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