Upregulation of CCR4 in activated CD8(+) T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection

Spoerl S, Kremer A, Aigner M, Eisenhauer N, Koch P, Meretuk L, Loeffler P, Tenbusch M, Maier C, Überla K, Heinzerling L, Frey B, Lutzny-Geier G, Winkler T, Krönke G, Vetter M, Bruns H, Neurath M, Mackensen A, Kremer A, Völkl S (2021)

Publication Type: Journal article

Publication year: 2021

Journal

European Journal of Immunology Wiley-VCH Verlag

DOI: 10.1002/eji.202049135

Abstract

COVID-19 is a life-threatening disease leading to bilateral pneumonia and respiratory failure. The underlying reasons why a smaller percentage of patients present with severe pulmonary symptoms whereas the majority is only mildly affected are to date not well understood.

Authors with CRIS profile

Anita Kremer Department of Medicine 5 – Haematology and Oncology Nina Eisenhauer Department of Medicine 5 – Haematology and Oncology Matthias Tenbusch Professur für Genbasierte Immunisierungsverfahren Klaus Überla Lehrstuhl für Klinische und Molekulare Virologie Lucie Heinzerling Department of Dermatology Benjamin Frey Department of Radiation Oncology Gloria Lutzny-Geier Department of Medicine 5 – Haematology and Oncology Thomas Winkler Professur für Genetik Gerhard Krönke Department of Medicine 3 – Rheumatology and Immunology Marcel Vetter Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Heiko Bruns Department of Medicine 5 – Haematology and Oncology Markus Neurath Lehrstuhl für Innere Medizin I Andreas Mackensen Lehrstuhl für Innere Medizin V Andreas Kremer Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Simon Völkl Department of Medicine 5 – Haematology and Oncology

How to cite

APA:

Spoerl, S., Kremer, A., Aigner, M., Eisenhauer, N., Koch, P., Meretuk, L.,... Völkl, S. (2021). Upregulation of CCR4 in activated CD8(+) T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection. European Journal of Immunology. https://doi.org/10.1002/eji.202049135

MLA:

Spoerl, Silvia, et al. "Upregulation of CCR4 in activated CD8(+) T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection." European Journal of Immunology (2021).

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