Intracellular Quantification and Localization of Label-Free Iron Oxide Nanoparticles by Holotomographic Microscopy

Friedrich RP, Schreiber E, Tietze R, Yang H, Pilarsky C, Alexiou C (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Nanotechnology, Science and Applications Dove Medical Press

Book Volume: 13

Pages Range: 119-130

DOI: 10.2147/NSA.S282204

Abstract

Background: The limitations of optical microscopy to determine the cellular localization of label-free nanoparticles prevent a solid prediction of the cellular effect of particles intended for medical applications. To avoid the strong physicochemical changes associated with fluorescent labelling, which often result in differences in cellular uptake, efficiency and toxicity of particles, novel detection techniques are required.

Authors with CRIS profile

Rainer Tietze Medizinische Fakultät Hai Yang Department of Surgery Christian Pilarsky Professur für Chirurgische Forschung Christoph Alexiou Professur für Nanomedizin

How to cite

APA:

Friedrich, R.P., Schreiber, E., Tietze, R., Yang, H., Pilarsky, C., & Alexiou, C. (2020). Intracellular Quantification and Localization of Label-Free Iron Oxide Nanoparticles by Holotomographic Microscopy. Nanotechnology, Science and Applications, 13, 119-130. https://dx.doi.org/10.2147/NSA.S282204

MLA:

Friedrich, Ralf P., et al. "Intracellular Quantification and Localization of Label-Free Iron Oxide Nanoparticles by Holotomographic Microscopy." Nanotechnology, Science and Applications 13 (2020): 119-130.

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