Rheological behavior of an artificial synovial fluid – influence of temperature, shear rate and pressure

Rothammer B, Marian M, Rummel F, Schroeder S, Uhler M, Kretzer JP, Tremmel S, Wartzack S (2021)

Publication Language: English

Publication Type: Journal article, Original article

Publication year: 2021

Journal

Journal of the Mechanical Behavior of Biomedical Materials Elsevier

Book Volume: 115

Pages Range: 1-8

Article Number: 104278

URI: https://www.archiv.mfk.tf.fau.de?file=pubmfk_5fda6d3c498ce

DOI: 10.1016/j.jmbbm.2020.104278

Abstract

Despite the excellent clinical performance of joint replacements, wear-induced aseptic loosening is a main cause of premature implant failure. Tribological testing is usually carried out using bovine serum as an artificial synovial fluid. In order to gain new insights into the suitability to simulate human synovial fluid and provide recommendations for the conditions of tribological testing, accurate rheological measurements on the influence of temperature, shear rate and pressure on density and viscosity were performed. Thus, a temperature dependence of density and viscosity could be verified, whereas both values decreased with higher temperatures. The temperature dependency of viscosity could be approximated by an Arrhenius model. Moreover, shear-thinning characteristics could be demonstrated and fitted to a Cross model, which agreed well with investigations on human synovial fluid reported in literature. Furthermore, an anomaly of pressure dependence of viscosity was found and correlated with the behavior of water as a main constituent. At room temperature, the viscosity initially decreased to a minimum and then increased again as a function of pressure. This was no longer distinct at human body temperatures. Consequently, the present study confirms the suitability of bovine serum as a substitute synovial fluid and emphasizes the importance of realistic testing conditions in order to ensure transferability and comparability.

Authors with CRIS profile

Benedict Rothammer Chair of Engineering Design Max Marian Chair of Engineering Design Sandro Wartzack Chair of Engineering Design

Involved external institutions

Universität Bayreuth DE Germany (DE) Universitätsklinikum Heidelberg DE Germany (DE) Anton Paar Germany GmbH DE Germany (DE)

How to cite

APA:

Rothammer, B., Marian, M., Rummel, F., Schroeder, S., Uhler, M., Kretzer, J.P.,... Wartzack, S. (2021). Rheological behavior of an artificial synovial fluid – influence of temperature, shear rate and pressure. Journal of the Mechanical Behavior of Biomedical Materials, 115, 1-8. https://dx.doi.org/10.1016/j.jmbbm.2020.104278

MLA:

Rothammer, Benedict, et al. "Rheological behavior of an artificial synovial fluid – influence of temperature, shear rate and pressure." Journal of the Mechanical Behavior of Biomedical Materials 115 (2021): 1-8.

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