Pulmonary rehabilitation in COPD: influence of comorbidities on physical activity

Limbach M, Wittmann M, Lehbert N, Geidl W, Carl J, Pfeifer K, Schultz K (2020)


Publication Type: Conference contribution

Publication year: 2020

DOI: 10.1183/13993003.congress-2020.87

Abstract

Background: Comorbidities (CM) in COPD patients affect the course of the disease and have consequences for the disease management. Only few data are available how physical activity (PA) is associated with CM. Aim is the determination of the influence of CM on PA in COPD patients.


Methods: Within the STAR-study PA (steps/day) was measured by triaxial accelerometry in COPD patients 2 weeks before (T0), 6 weeks (T3) and 6 months (T4) after pulmonary rehabilitation (PR). We determined CM and conducted a regression analyses. Dependent variable is the PA at T0 and the change T0-T3, T0-T4 and T3-T4. Predictors are: age, gender, obesity, cachexia, hypertension, left heart failure, depression, asthma and degenerative spinal syndromes. T-tests were used to calculate mean differences.


Results: 205 COPD patients (mean age 57.7±4.7; male=71.2%; FEV%pred 60.3%±19.4; GOLD 1,2,3,4=10.8%, 45.3%, 36.0%, 7.6%) were analyzed.The PA after PR increases significantly from both T0-T3 and T0-T4. T3-T4 shows a significant decrease. Cardiovascular CM (64.4%) were most frequent, followed by orthopedic (63.5%), mental (20.0%) and other pulmonary CM (24.4%). Adiposity was found in 36.1% and cachexia in 9.3% of the patients. PA at T0 is significantly influenced (p<.05) by asthma (ß=-.231) and left heart failure (ß=-.176). No significant analyses are available regarding T0-T3, T0-T4 and T3-T4.


Discussion: There is a high amount of COPD patients with CM, even in a comparatively young and mostly working population. CM should be diagnostically assessed and also therapeutically considered in the PR. They are no contraindication for a successful PR. Numerical, cardiac and orthopedic CM and obesity are of particular practical relevance.

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How to cite

APA:

Limbach, M., Wittmann, M., Lehbert, N., Geidl, W., Carl, J., Pfeifer, K., & Schultz, K. (2020). Pulmonary rehabilitation in COPD: influence of comorbidities on physical activity. In European Respiratory Society (Eds.), Proceedings of the ERS International Congress.

MLA:

Limbach, Matthias, et al. "Pulmonary rehabilitation in COPD: influence of comorbidities on physical activity." Proceedings of the ERS International Congress Ed. European Respiratory Society, 2020.

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