Dual-beam laser traps in biology and medicine: When one beam is not enough

Whyte G, Lautenschlaeger F, Kreysing M, Boyde L, Ekpenyong A, Delabre U, Chalut K, Franze K, Guck J (2010)


Publication Type: Conference contribution

Publication year: 2010

Journal

Book Volume: 7762

Conference Proceedings Title: Proceedings of SPIE - The International Society for Optical Engineering

ISBN: 9780819482587

DOI: 10.1117/12.862928

Abstract

Optical traps are nowadays quite ubiquitous in biophysical and biological studies. The term is often used synonymously with optical tweezers, one particular incarnation of optical traps. However, there is another kind of optical trap consisting of two non-focused, counter-propagating laser beams. This dual-beam trap predates optical tweezers by almost two decades and currently experiences a renaissance. The advantages of dual-beam traps include lower intensities on the trapped object, decoupling from imaging optics, and the possibility to trap cells and cell clusters up to 100 microns in diameter. When used for deforming cells this trap is referred to as an optical stretcher. I will review several applications of such traps in biology and medicine for the detection of cancer cells, sorting stem cells, testing light guiding properties of retinal cells and the controlled rotation of cells for single cell tomography. © 2010 SPIE.

Authors with CRIS profile

Involved external institutions

How to cite

APA:

Whyte, G., Lautenschlaeger, F., Kreysing, M., Boyde, L., Ekpenyong, A., Delabre, U.,... Guck, J. (2010). Dual-beam laser traps in biology and medicine: When one beam is not enough. In Proceedings of SPIE - The International Society for Optical Engineering.

MLA:

Whyte, Graeme, et al. "Dual-beam laser traps in biology and medicine: When one beam is not enough." Proceedings of the Optical Trapping and Optical Micromanipulation VII 2010.

BibTeX: Download