Atomic force microscopy and its contribution to understanding the development of the nervous system
Franze K (2011)
Publication Type: Journal article, Review article
Publication year: 2011
Journal
Book Volume: 21
Pages Range: 530-537
Journal Issue: 5
DOI: 10.1016/j.gde.2011.07.001
Abstract
While our understanding of the influence of biochemical signaling on cell functioning is increasing rapidly, the consequences of mechanical signaling are currently poorly understood. However, cells of the nervous system respond to their mechanical environment; their mechanosensitivity has important implications for development and disease. Atomic force microscopy provides a powerful technique to investigate the mechanical interaction of cells with their environment with high resolution. This method can be used to obtain high-resolution surface topographies, stiffness maps, and apply well-defined forces to samples at different length scales. This review summarizes recent advances of atomic force microscopy, provides an overview about state-of-the-art measurements, and suggests directions for future applications to investigate the involvement of mechanics in the development of the nervous system. © 2011 Elsevier Ltd.
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United Kingdom (GB)How to cite
APA:
Franze, K. (2011). Atomic force microscopy and its contribution to understanding the development of the nervous system. Current Opinion in Genetics & Development, 21(5), 530-537. https://dx.doi.org/10.1016/j.gde.2011.07.001
MLA:
Franze, Kristian. "Atomic force microscopy and its contribution to understanding the development of the nervous system." Current Opinion in Genetics & Development 21.5 (2011): 530-537.
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