Complex stiffness gradient substrates for studying mechanotactic cell migration
Kuo CHR, Xian J, Brenton JD, Franze K, Sivaniah E (2012)
Publication Type: Journal article
Publication year: 2012
Journal
Book Volume: 24
Pages Range: 6059-6064
Journal Issue: 45
Abstract
Polyacrylamide gels are cast upon a stiff support with controlled topography, resulting in a thin gel layer of variable height. The topographical profiles project a stiffness map onto the gel, resulting in controlled linear and non-linear 2D stiffness gradients. Fibroblasts, which migrate towards stiffer substrates, accumulate in areas with a gel thickness below 15 μm. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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APA:
Kuo, C.-H.R., Xian, J., Brenton, J.D., Franze, K., & Sivaniah, E. (2012). Complex stiffness gradient substrates for studying mechanotactic cell migration. Advanced Materials, 24(45), 6059-6064. https://doi.org/10.1002/adma.201202520
MLA:
Kuo, Cheng-Hwa R., et al. "Complex stiffness gradient substrates for studying mechanotactic cell migration." Advanced Materials 24.45 (2012): 6059-6064.
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