Atomic force microscopy-based force measurements on animal cells and tissues
Gautier HOB, Thompson AJ, Achouri S, Koser DE, Holtzmann K, Moeendarbary E, Franze K (2015)
Publication Type: Book chapter / Article in edited volumes
Publication year: 2015
Journal
Publisher: Academic Press Inc.
Edited Volumes: Methods in Cell Biology
Book Volume: 125
Pages Range: 211-235
DOI: 10.1016/bs.mcb.2014.10.005
Abstract
During development, normal functioning, as well as in certain pathological conditions, cells are influenced not only by biochemical but also by mechanical signals. Over the past two decades, atomic force microscopy (AFM) has become one of the key tools to investigate the mechanical properties and interactions of biological samples. AFM studies have provided important insights into the role of mechanical signaling in different biological processes. In this chapter, we introduce different applications of AFM-based force measurements, from experimental setup and sample preparation to data acquisition and analysis, with a special focus on nervous system mechanics. Combined with other microscopy techniques, AFM is a powerful tool to reveal novel information about molecular, cell, and tissue mechanics.
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United Kingdom (GB)How to cite
APA:
Gautier, H.O.B., Thompson, A.J., Achouri, S., Koser, D.E., Holtzmann, K., Moeendarbary, E., & Franze, K. (2015). Atomic force microscopy-based force measurements on animal cells and tissues. In Methods in Cell Biology. (pp. 211-235). Academic Press Inc..
MLA:
Gautier, Helene O. B., et al. "Atomic force microscopy-based force measurements on animal cells and tissues." Methods in Cell Biology. Academic Press Inc., 2015. 211-235.
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