Engelke K, Chaudry O, Nagel AM (2020)
Publication Type: Journal article
Publication year: 2020
Book Volume: 29
Pages Range: 132-142
Journal Issue: 2
DOI: 10.1055/a-1130-4462
This article provides an overview of magnetic resonance imaging (MRI) based methods for the quantification of muscle degeneration. In addition to muscle volume, Dixon imaging can be used to determine the percentage of fat. In addition, there are approaches to visualize and quantify early signs of degeneration via the distribution of the degree of inflammation or the sodium concentration of the muscle. Except for sodium imaging, these methods are routinely used for diagnosis and follow-up in muscle diseases. In osteology and gerontology, the importance of the muscle-bone unit for fracture prediction and frailty in old age is routinely emphasized, but degeneration of the muscles is mainly recorded via extrinsic parameters such as muscle strength and function. Frequently used intrinsic parameters such as DXA lean mass or muscle volume determined with CT or MRI correlate only moderately with extrinsic parameters. However, a more precise characterization of muscle quality should remedy this shortcoming. Appropriate methods are available with CT and MRI, but these must now be used in studies on age-related muscle degeneration, in intervention studies and in studies on fracture risk assessment.
APA:
Engelke, K., Chaudry, O., & Nagel, A.M. (2020). Quantitative MR-Bildgebung zur Charakterisierung der Skelettmuskulatur. Osteologie, 29(2), 132-142. https://dx.doi.org/10.1055/a-1130-4462
MLA:
Engelke, Klaus, Oliver Chaudry, and Armin Michael Nagel. "Quantitative MR-Bildgebung zur Charakterisierung der Skelettmuskulatur." Osteologie 29.2 (2020): 132-142.
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