Synthesis and characterization of rubidium-containing bioactive glass nanoparticles
Ouyang S, Zheng K, Huang Q, Liu Y, Boccaccini AR (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 273
Article Number: 127920
DOI: 10.1016/j.matlet.2020.127920
Abstract
Developing bioactive glass nanoparticles (BGNs) comprising biologically active ions is a promising strategy to enhance therapeutic performance. Given the pro-osteogenic activity of rubidium (Rb), a new type of Rb-containing BGNs was developed in this work. Here, a modified Stӧber method was employed to synthesize monodispersed spherical BGNs (particle size ~ 100 nm) with different contents of Rb incorporation (nominal 1, 3 and 5 at.%). The results showed that Rb incorporation did not significantly affect the size, shape and amorphous characteristic of BGNs. The real Rb contents (maximum 0.62 at.%) in BGNs were much lower than the designed ones. Compared with Rb-free BGNs, Rb-BGNs exhibited enhanced hydroxyapatite-forming ability in simulated body fluid. The results suggest that Rb-BGNs are promising to be used as bioactive fillers for bone regeneration applications.
Authors with CRIS profile
Kai Zheng
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Aldo Boccaccini
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Involved external institutions
China (CN)How to cite
APA:
Ouyang, S., Zheng, K., Huang, Q., Liu, Y., & Boccaccini, A.R. (2020). Synthesis and characterization of rubidium-containing bioactive glass nanoparticles. Materials Letters, 273. https://dx.doi.org/10.1016/j.matlet.2020.127920
MLA:
Ouyang, Sihui, et al. "Synthesis and characterization of rubidium-containing bioactive glass nanoparticles." Materials Letters 273 (2020).
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