Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI

Linder V, Fritscher T, Hammon M, Schroth M, Schmidt W, Uder M, Rompel O (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Radiology Case Reports Elsevier

Book Volume: 15

Pages Range: 761-764

Journal Issue: 6

DOI: 10.1016/j.radcr.2020.03.019

Abstract

Background: Metastatic osteosarcoma with direct cardiac involvement is an exceptionally rare finding. Reliable detection of cardiac metastases is known to be crucial for patients therapy and prognosis. Case Summary: In a 10-year-old boy affected by osteosarcoma of the left femur, a baseline Fluorine-18-fluorodeoxy-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) was performed to assess the full extent of disease. Whole-body scan detected numerous bone metastases together with a single pulmonary metastasis. Moreover, increased tracer uptake was observed in the intracavitary right cardiac ventricle in the position of a subtle spot of calcification. Because of nondetectability of a cavitary lesion on echocardiography, cardiac magnetic resonance imaging (CMRI) examination was performed to evaluate cardiac 18F-FDG PET/CT finding. CMRI revealed a small nodule in the right ventricle attached to the trabeculae, highly suspicious of a direct cardiac metastasis. After 4 cycles of chemotherapy, complete regression of tracer uptake of the lesion was observed on a follow-up 18F-FDG PET/CT scan. Conclusion: CMRI is able to detect even small, clinically asymptomatic cardiac metastases in young patients affected by osteosarcoma.

Authors with CRIS profile

Matthias Hammon Institute of Radiology Michael Uder Lehrstuhl für Diagnostische Radiologie

Involved external institutions

Cnopf'sche Kinderklinik DE Germany (DE) Paracelsus Medizinische Privatuniversität, Nürnberg DE Germany (DE)

How to cite

APA:

Linder, V., Fritscher, T., Hammon, M., Schroth, M., Schmidt, W., Uder, M., & Rompel, O. (2020). Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI. Radiology Case Reports, 15(6), 761-764. https://dx.doi.org/10.1016/j.radcr.2020.03.019

MLA:

Linder, Verena, et al. "Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI." Radiology Case Reports 15.6 (2020): 761-764.

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