Moving exercise research in multiple sclerosis forward (the MoXFo initiative): Developing consensus statements for research

Dalgas U, Hvid LG, Kwakkel G, Motl RW, de Groot V, Feys P, Op’t Eijnde B, Coote S, Beckerman H, Pfeifer K, Streber R, Peters S, Riemann-Lorenz K, Rosenkranz SC, Centonze D, Van Asch P, Bansi J, Sandroff BM, Pilutti LA, Ploughman M, Freeman J, Paul L, Dawes H, Romberg A, Kalron A, Stellmann JP, Friese MA, Heesen C (2020)

Publication Type: Journal article

Publication year: 2020

Journal

DOI: 10.1177/1352458520910360

Abstract

Exercise as a subset of physical activity is a cornerstone in the management of multiple sclerosis (MS) based on its pleotropic effects. There is an exponential increase in the quantity of research on exercise in MS, yet a number of barriers associated with study content and quality hamper rapid progress in the field. To address these barriers and accelerate discovery, a new international partnership of MS-related experts in exercise has emerged with the goal of advancing the research agenda. As a first step, the expert panel met in May 2018 and identified the most urgent areas for moving the field forward, and discussed the framework for such a process. This led to identification of five themes, namely “Definitions and terminology,” “Study methodology,” “Reporting and outcomes,” “Adherence to exercise,” and “Mechanisms of action.” Based on the identified themes, five expert groups have been formed, that will further (a) outline the challenges per theme and (b) provide recommendations for moving forward. We aim to involve and collaborate with people with MS/MS organizations (e.g. Multiple Sclerosis International Federation (MSIF) and European Multiple Sclerosis Platform (EMSP)) in all of these five themes. The generation of this thematic framework with multi-expert perspectives can bolster the quality and scope of exercise studies in MS that may ultimately improve the daily lives of people with MS.

Authors with CRIS profile

Involved external institutions

University of Plymouth United Kingdom (GB) Kliniken Valens Switzerland (CH) Masku Neurological Rehabilitation Center / Maskun neurologinen kuntoutuskeskus Finland (FI) University of Limerick Ireland (IE) Hôpital de la Timone France (FR) Universitätsklinikum Hamburg-Eppendorf (UKE) Germany (DE) Memorial University of Newfoundland (MUN) Canada (CA) IRCCS Istituto Neurologico Mediterraneo Neuromed Italy (IT) University of Alabama at Birmingham (UAB) United States (USA) (US) Amsterdam University Medical Centers (Amsterdam UMC) / Amsterdam Universitair Medische Centra Netherlands (NL) University of Ottawa Canada (CA) Vrije Universiteit Amsterdam (VU) / University Amsterdam Netherlands (NL) Hasselt University / Universiteit Hasselt Belgium (BE) Glasgow Caledonian University (GCU) United Kingdom (GB) Aarhus University Denmark (DK) Deutscher Verband für Gesundheitssport & Sporttherapie (DVGS) e.V. Germany (DE) Tel Aviv University Israel (IL) Oxford Brookes University United Kingdom (GB)

How to cite

APA:

Dalgas, U., Hvid, L.G., Kwakkel, G., Motl, R.W., de Groot, V., Feys, P.,... Heesen, C. (2020). Moving exercise research in multiple sclerosis forward (the MoXFo initiative): Developing consensus statements for research. Multiple sclerosis journal. https://dx.doi.org/10.1177/1352458520910360

MLA:

Dalgas, Ulrik, et al. "Moving exercise research in multiple sclerosis forward (the MoXFo initiative): Developing consensus statements for research." Multiple sclerosis journal (2020).

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