Slany R (2020)
Publication Type: Journal article, Review article
Publication year: 2020
Book Volume: 1863
Article Number: 194503
Journal Issue: 3
DOI: 10.1016/j.bbagrm.2020.194503
The highly leukemogenic MLL fusion proteins have a unique mechanism of action. This review summarizes the current knowledge of how MLL fusions interact with the transcriptional machinery and it proposes a hypothesis how these proteins modify transcriptional control to act as transcriptional amplifiers causing runaway production of certain RNAs that transform hematopoietic cells.
APA:
Slany, R. (2020). MLL fusion proteins and transcriptional control. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms, 1863(3). https://dx.doi.org/10.1016/j.bbagrm.2020.194503
MLA:
Slany, Robert. "MLL fusion proteins and transcriptional control." Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms 1863.3 (2020).
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