Phosphate glass fibres with therapeutic ions release capability–a review
Lapa A, Cresswell M, Jackson P, Boccaccini AR (2020)
Publication Type: Journal article, Review article
Publication year: 2020
Journal
Book Volume: 119
Pages Range: 1-14
Journal Issue: 1
DOI: 10.1080/17436753.2018.1564413
Abstract
Phosphate-based glasses (PBG) have low melting temperatures and can be obtained by melt-quenching and sol-gel methods. The most significant characteristic of PBG is their ability to dissolve completely in aqueous solution within different timeframes. This solubility can reduce the need for revision surgeries and makes PBG well-suited for soft tissue regeneration. Phosphate glass fibres (PGF) due to their geometry and volume–surface area ratio are the subject of a growing number of studies on resorbable composites. Medical applications include bone fixation devices, nerve tissue scaffolds and wound healing. PBG can be doped with various ions to enhance their biological, chemical and structural properties allowing the preparation of fibres with designed properties and with the ability to release biologically active ions upon degradation. The aim of this review is to look in detail at the influence of different dopants on PGF behaviour, both at a structural and biological level.
Authors with CRIS profile
Agata Lapa
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Aldo Boccaccini
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Involved external institutions
United Kingdom (GB)How to cite
APA:
Lapa, A., Cresswell, M., Jackson, P., & Boccaccini, A.R. (2020). Phosphate glass fibres with therapeutic ions release capability–a review. Advances in Applied Ceramics, 119(1), 1-14. https://dx.doi.org/10.1080/17436753.2018.1564413
MLA:
Lapa, Agata, et al. "Phosphate glass fibres with therapeutic ions release capability–a review." Advances in Applied Ceramics 119.1 (2020): 1-14.
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