Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration

Zivanovic J, Kouroussis E, Kohl JB, Adhikari B, Bursac B, Schott-Roux S, Petrovic D, Miljkovic JL, Thomas-Lopez D, Jung Y, Miler M, Mitchell S, Milosevic V, Gomes JE, Benhar M, Gonzales-Zorn B, Ivanovic-Burmazovic I, Torregrossa R, Mitchell JR, Whiteman M, Schwarz G, Snyder SH, Paul BD, Carroll KS, Filipovic MR (2019)


Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 30

Pages Range: 1152-1170.e13

Journal Issue: 6

DOI: 10.1016/j.cmet.2019.10.007

Abstract

Zivanovic et al. develop a robust method for chemoselective persulfide labeling using dimedone-based probes to show that persulfidation is an evolutionarily conserved post-translational modification used by the cells to protect proteins from overoxidation caused by different stressors. Higher persulfidation levels, caused by pharmacological or dietary interventions, lead to better resistance to oxidative stress and longer life.

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APA:

Zivanovic, J., Kouroussis, E., Kohl, J.B., Adhikari, B., Bursac, B., Schott-Roux, S.,... Filipovic, M.R. (2019). Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metabolism, 30(6), 1152-1170.e13. https://doi.org/10.1016/j.cmet.2019.10.007

MLA:

Zivanovic, Jasmina, et al. "Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration." Cell Metabolism 30.6 (2019): 1152-1170.e13.

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