Biolubrication synergy: Hyaluronan – Phospholipid interactions at interfaces

Dėdinaitė A, Wieland DC, Beldowski P, Claesson PM (2019)

Publication Type: Journal article, Review article

Publication year: 2019

Journal

Advances in Colloid and Interface Science Elsevier

Book Volume: 274

Article Number: 102050

DOI: 10.1016/j.cis.2019.102050

Abstract

The manner in which nature has solved lubrication issues has fascinated scientists for centuries, in particular when considering that lubrication is achieved in aqueous media. The most outstanding system in this respect is likely the synovial joint, where close to frictionless motion is realized under different loads and shear rates. This review article focuses on two components present in the synovial area, hyaluronan and phospholipids. We recapitulate what has been learned about their interactions at interfaces from recent experiments, with focus on results obtained using reflectivity techniques at large scale facilities. In parallel, modelling experiments have been carried out and from these efforts new detailed knowledge about how hyaluronan and phospholipids interact has been gained. In this review we combine findings from modelling and experiments to gain deeper insight. Finally, we summarize what has been learned of the lubrication performance of mixtures of phospholipids and hyaluronan.

Authors with CRIS profile

Piotr Beldowski Lehrstuhl für Multiscale Simulation of Particulate Systems

Involved external institutions

Royal Institute of Technology / Kungliga Tekniska Högskolan (KTH) SE Sweden (SE) Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (HZG) DE Germany (DE)

How to cite

APA:

Dėdinaitė, A., Wieland, D.C., Beldowski, P., & Claesson, P.M. (2019). Biolubrication synergy: Hyaluronan – Phospholipid interactions at interfaces. Advances in Colloid and Interface Science, 274. https://dx.doi.org/10.1016/j.cis.2019.102050

MLA:

Dėdinaitė, Andra, et al. "Biolubrication synergy: Hyaluronan – Phospholipid interactions at interfaces." Advances in Colloid and Interface Science 274 (2019).

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