Red light-triggered nucleic acid-templated reaction based on cyclic oligonucleotide substrates

Zozulia O, Bachmann T, Deussner-Helfmann NS, Beierlein F, Heilemann M, Mokhir A (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Chemical Communications Royal Society of Chemistry

Book Volume: 55

Pages Range: 10713-10716

Journal Issue: 72

DOI: 10.1039/c9cc03587g

Abstract

A red light-triggered reaction based on cyclic oligonucleotide substrates that is accelerated over 30-fold by specific nucleic acid templates and generates a bright fluorescent probe was developed. We confirmed that this reaction is compatible with fluorescence correlation spectroscopy (FCS) thereby allowing detection of nucleic acids down to 1 nM.

Authors with CRIS profile

Oleksii Zozulia Lehrstuhl für Organische Chemie II Tobias Bachmann Lehrstuhl für Organische Chemie II Frank Beierlein Computer-Chemie-Centrum Andriy Mokhir Professur für Organische Chemie

Involved external institutions

Goethe-Universität Frankfurt am Main

Germany (DE)

How to cite

APA:

Zozulia, O., Bachmann, T., Deussner-Helfmann, N.S., Beierlein, F., Heilemann, M., & Mokhir, A. (2019). Red light-triggered nucleic acid-templated reaction based on cyclic oligonucleotide substrates. Chemical Communications, 55(72), 10713-10716. https://dx.doi.org/10.1039/c9cc03587g

MLA:

Zozulia, Oleksii, et al. "Red light-triggered nucleic acid-templated reaction based on cyclic oligonucleotide substrates." Chemical Communications 55.72 (2019): 10713-10716.

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