Setting mechanism of a CDHA forming α-TCP cement modified with sodium phytate for improved injectability

Journal article


Publication Details

Author(s): Weichhold J, Gbureck U, Götz-Neunhoeffer F, Hurle K
Journal: Materials
Publication year: 2019
Volume: 12
Journal issue: 13
ISSN: 1996-1944


Abstract

A calcium deficient hydroxyapatite (CDHA) forming cement with a bimodal grain size distribution, composed of α-TCP and fine grained CDHA at a weight ratio of 9:1, was modified by the addition of sodium phytate (IP6) in variable amounts ranging from 0.25 to 2 wt.%, related to the powder content. The injectability of the cement paste was drastically increased by the IP6 addition, independent of the amount of added IP6. Additionally, the cement paste viscosity during the first minutes decreased. These effects could be clearly related to a slightly more negative zeta potential. Furthermore, IP6 was shown to strongly retard the setting reaction, as can be seen both in the calorimetry and X-ray diffraction measurements. In addition, octacalcium phosphate (OCP) was identified as a further setting product. All measurements were performed at 23 °C and 37 °C to assess the effect of temperature on the setting reaction for both clinical handling by the surgeon and the final hardening in the bone defect.


FAU Authors / FAU Editors

Götz-Neunhoeffer, Friedlinde Prof. Dr.
Lehrstuhl für Mineralogie
Hurle, Katrin Dr.
Lehrstuhl für Mineralogie


External institutions with authors

Julius-Maximilians-Universität Würzburg


How to cite

APA:
Weichhold, J., Gbureck, U., Götz-Neunhoeffer, F., & Hurle, K. (2019). Setting mechanism of a CDHA forming α-TCP cement modified with sodium phytate for improved injectability. Materials, 12(13). https://dx.doi.org/10.3390/ma12132098

MLA:
Weichhold, Jan, et al. "Setting mechanism of a CDHA forming α-TCP cement modified with sodium phytate for improved injectability." Materials 12.13 (2019).

BibTeX: 

Last updated on 2019-19-07 at 15:08