Anelastic reorganisation of fibre-reinforced biological tissues

Beitrag in einer Fachzeitschrift

Details zur Publikation

Autorinnen und Autoren: Di Stefano S, Carfagna M, Knodel M, Hashlamoun K, Federico S, Grillo A
Zeitschrift: Computing and Visualization in Science
Jahr der Veröffentlichung: 2019
ISSN: 1432-9360
eISSN: 1433-0369


In this work, we contribute to the study of the structural reorganisation of biological tissues in response to mechanical stimuli. We specialise our investigation to a class of hydrated soft tissues, whose internal structure features reinforcing fibres. These are oriented statistically within the tissue, and their pattern of orientation is such that, at each material point, the tissue is anisotropic. From its natural, stress-free state, the tissue can be distorted anelastically into a global reference configuration, and then deformed under the action of external mechanical loads. The anelastic distortions are responsible for changing irreversibly the internal structure of the tissue, which, in the present context, occurs through both the rearrangement of the bonds among the tissue cells and the deformation-driven reorientation of the fibres. The anelastic strains, in addition, are assumed to model the onset and evolution of microcracks in the tissue, which may be triggered by the mechanical loads applied to the tissue in the case of traumatic events, or diseases. For our purposes, we formulate an anisotropic model of remodelling and we consider a fully isotropic model of structural reorganisation for comparison, with the aim to study if, how, and to what extent the evolution of anelastic distortions is influenced by the tissue’s anisotropy.

FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Knodel, Markus Dr.
Lehrstuhl für Angewandte Mathematik (Modellierung und Numerik)

Einrichtungen weiterer Autorinnen und Autoren

Politecnico di Torino
University of Calgary


Di Stefano, S., Carfagna, M., Knodel, M., Hashlamoun, K., Federico, S., & Grillo, A. (2019). Anelastic reorganisation of fibre-reinforced biological tissues. Computing and Visualization in Science.

Di Stefano, Salvatore, et al. "Anelastic reorganisation of fibre-reinforced biological tissues." Computing and Visualization in Science (2019).


Zuletzt aktualisiert 2019-16-07 um 08:38