Genomic analysis of a novel nontoxigenic Corynebacterium diphtheriae strain isolated from a cancer patient

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autorinnen und Autoren: Ramdhan ND, Blom J, Sutcliffe IC, Pereira-Ribeiro PM, Santos CS, Mattos-Guaraldi AL, Burkovski A, Sangal V
Zeitschrift: New Microbes and New Infections
Jahr der Veröffentlichung: 2019
Band: 30
ISSN: 2052-2975


Abstract

The genome of a novel nontoxigenic Corynebacterium diphtheriae, strain 5015, isolated from a patient with adenoid cystic carcinoma was sequenced and compared with 117 publically available genomes. This strain is phylogenetically distinct and lacks virulence genes encoding the toxin, BigA and Sdr-like adhesins. Strain 5015 possesses spaD-type and spaH-type pilus gene clusters with a loss of some gene functions, and 31 unique genes that need molecular characterization to understand their potential role in virulence characteristics.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Burkovski, Andreas Prof. Dr.
Professur für Mikrobiologie


Einrichtungen weiterer Autorinnen und Autoren

Kerckhoff-Klinik
Northumbria University
Rio de Janeiro State University / Universidade do Estado do Rio de Janeiro (UERJ)


Zitierweisen

APA:
Ramdhan, N.D., Blom, J., Sutcliffe, I.C., Pereira-Ribeiro, P.M., Santos, C.S., Mattos-Guaraldi, A.L.,... Sangal, V. (2019). Genomic analysis of a novel nontoxigenic Corynebacterium diphtheriae strain isolated from a cancer patient. New Microbes and New Infections, 30. https://dx.doi.org/10.1016/j.nmni.2019.100544

MLA:
Ramdhan, N. D., et al. "Genomic analysis of a novel nontoxigenic Corynebacterium diphtheriae strain isolated from a cancer patient." New Microbes and New Infections 30 (2019).

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Zuletzt aktualisiert 2019-10-05 um 09:01