Exploration of different x-ray Talbot-Lau setups for dark-field lung imaging examined in a porcine lung

Journal article


Publication Details

Author(s): Ludwig V, Seifert M, Hauke C, Hellbach K, Horn F, Pelzer G, Radicke M, Rieger J, Sutter SM, Michel T, Anton G
Journal: Physics in Medicine and Biology
Publication year: 2019
Volume: 64
Journal issue: 6
ISSN: 0031-9155


Abstract

X-ray dark-field imaging is a promising technique for lung diagnosis. Due to the alveolar structure of lung tissue, a higher contrast is obtained by the dark-field image compared to the attenuation image. Animal studies indicate an enhancement regarding the detection of lung diseases in early stages. In this publication, we focus on the influence of different Talbot-Lau interferometer specifications while maintaining the x-ray source, sample magnification and detector system. By imaging the same porcine lung with three different grating sets, we analyze the contrast-to-noise ratio of the obtained dark-field images with respect to visibility and correlation length. We demonstrate that relatively large grating periods of the phase and of the analyzer grating are sufficient for high quality lung imaging at reasonable dose levels.


FAU Authors / FAU Editors

Anton, Gisela Prof. Dr.
Lehrstuhl für Experimentalphysik (Teilchen- und Astroteilchenphysik)
Hauke, Christian
Lehrstuhl für Experimentalphysik (Teilchen- und Astroteilchenphysik)
Horn, Florian
Lehrstuhl für Experimentalphysik (Teilchen- und Astroteilchenphysik)
Ludwig, Veronika
Lehrstuhl für Experimentalphysik (Teilchen- und Astroteilchenphysik)
Michel, Thilo PD Dr.
Lehrstuhl für Experimentalphysik (Teilchen- und Astroteilchenphysik)
Pelzer, Georg
Lehrstuhl für Experimentalphysik (Teilchen- und Astroteilchenphysik)
Rieger, Jens
Lehrstuhl für Experimentalphysik (Teilchen- und Astroteilchenphysik)
Seifert, Maria
Lehrstuhl für Experimentalphysik (Teilchen- und Astroteilchenphysik)


External institutions with authors

Ludwig-Maximilians-Universität (LMU)
Siemens AG, Healthcare Sector


How to cite

APA:
Ludwig, V., Seifert, M., Hauke, C., Hellbach, K., Horn, F., Pelzer, G.,... Anton, G. (2019). Exploration of different x-ray Talbot-Lau setups for dark-field lung imaging examined in a porcine lung. Physics in Medicine and Biology, 64(6). https://dx.doi.org/10.1088/1361-6560/ab051c

MLA:
Ludwig, Veronika, et al. "Exploration of different x-ray Talbot-Lau setups for dark-field lung imaging examined in a porcine lung." Physics in Medicine and Biology 64.6 (2019).

BibTeX: 

Last updated on 2019-29-03 at 22:08