Misleading debate – incidental findings in genomic research

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Details zur Publikation

Autorinnen und Autoren: Schuol S
Jahr der Veröffentlichung: 2017
Sprache: Englisch


Abstract

Since mutations with health relevance exist (2% in population with European ancestry - Amendola et al. 2015) why are these mutations not found incidentally? In contrast to med imaging, even a trained researcher cannot “see” IFs in genomic sequence. Owing to the complexity of genomic data, bioinformatic filters are necessary that avoid detection of incidental findings.

General conclusion: The debate on IFs in genomic research was a waste of cognitive, financial and psychological resources. Two steps to prevent such debates in future: 1. Early solution-development for plausible scenarios. 2. Then when empirical data is available – evaluation whether these projections remain true. The scenario has to be substantiated or, if necessary, corrected.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Schuol, Sebastian Dr.
Zentralinstitut für Wissenschaftsreflexion und Schlüsselqualifikationen (ZIWIS)


Zitierweisen

APA:
Schuol, S. (2017). Misleading debate – incidental findings in genomic research. In Proceedings of the Perspectives on scientific errors. TILPS - Tilburg University, NL.

MLA:
Schuol, Sebastian. "Misleading debate – incidental findings in genomic research." Proceedings of the Perspectives on scientific errors, TILPS - Tilburg University 2017.

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Zuletzt aktualisiert 2019-16-04 um 02:23