Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL knowledge hub project

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autorinnen und Autoren: Correa-Perez A, Abraha I, Cherubini A, Collinson A, Dardevet D, De Groot LCPGM, De Van Der Schueren MAE, Hebestreit A, Hickson M, Jaramillo-Hidalgo J, Lozano-Montoya I, O'Mahony D, Soiza RL, Visser M, Volkert D, Wolters M, Cruz Jentoft AJ
Zeitschrift: Ageing Research Reviews
Jahr der Veröffentlichung: 2019
Band: 49
Seitenbereich: 27-48
ISSN: 1568-1637


Abstract

INTRODUCTION: We aimed to perform a review of SRs of non-pharmacological interventions in older patients with well-defined malnutrition using relevant outcomes agreed by a broad panel of experts.
METHODS: PubMed, Cochrane, EMBASE, and CINHAL databases were searched for SRs. Primary studies from those SRs were included. Quality assessment was undertaken using Cochrane and GRADE criteria.
RESULTS: Eighteen primary studies from seventeen SRs were included. Eleven RCTs compared oral nutritional supplementation (ONS) with usual care. No beneficial effects of ONS treatment, after performing two meta-analysis in body weight changes (six studies), mean difference: 0.59 (95%CI -0.08, 1.96) kg, and in body mass index changes (two studies), mean difference: 0.31 (95%CI -0.17, 0.79) kg/m2 were found. Neither in MNA scores, muscle strength, activities of daily living, timed Up&Go, quality of life and mortality. Results of other intervention studies (dietary counselling and ONS, ONS combined with exercise, nutrition delivery systems) were inconsistent. The overall quality of the evidence was very low due to risk of bias and small sample size.
CONCLUSIONS: This review has highlighted the lack of high quality evidence to indicate which interventions are effective in treating malnutrition in older people. High quality research studies are urgently needed in this area.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Volkert, Dorothee Prof. Dr. rer. nat.
Professur für Klinische Ernährung im Alter


Einrichtungen weiterer Autorinnen und Autoren

Hogeschool van Arnhem en Nijmegen
Hospital de la Cruz Roja San José y Santa Adela
Hospital Universitario Ramón y Cajal
Istituto Nazionale di Riposo e Cura per Anziani (IRCCS INRCA)
Leibniz-Institut für Präventionsforschung und Epidemiologie - BIPS GmbH
NHS Grampian
South Infirmary Victoria University Hospital
Université d'Auvergne Clermont-Ferrand I / University of Auvergne
University of Plymouth
Vrije Universiteit Amsterdam (VU) / University Amsterdam
Wageningen University & Research


Zitierweisen

APA:
Correa-Perez, A., Abraha, I., Cherubini, A., Collinson, A., Dardevet, D., De Groot, L.C.P.G.M.,... Cruz Jentoft, A.J. (2019). Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL knowledge hub project. Ageing Research Reviews, 49, 27-48. https://dx.doi.org/10.1016/j.arr.2018.10.011

MLA:
Correa-Perez, Andrea, et al. "Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL knowledge hub project." Ageing Research Reviews 49 (2019): 27-48.

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Zuletzt aktualisiert 2019-28-02 um 22:08