Hydration mechanism of a calcium phosphate cement modified with phytic acid

Journal article
(Original article)


Publication Details

Author(s): Hurle K, Weichhold J, Brueckner M, Gbureck U, Brueckner T, Götz-Neunhoeffer F
Journal: Acta Biomaterialia
Publisher: Acta Materialia Inc
Publication year: 2018
Volume: 80
Pages range: 378-389
ISSN: 1742-7061


Abstract

Calcium phosphate cements composed of β-tricalcium phosphate (β-TCP) and phosphoric acid were modified by addition of 5, 10, 12.5, 15 and 20 wt% phytic acid (IP6) related to the β-TCP content and compared to a reference containing 0.5 M citric acid monohydrate solution as setting regulator. The hydration reaction of these cements was investigated by isothermal calorimetry and in-situ X-ray diffraction at 23 °C and 37 °C. The cements were further characterized with respect to their injectability, rheology, zeta potential and time-resolved compressive strength development.

Injectability was strongly improved by IP6 addition, while the maximum effect was already reached by the addition of 5 wt% IP6. This could be clearly related to an increase of the negative zeta potential leading to a mutual repulsion of cement particles. A further increase of the IP6 content had a detrimental effect on initial paste viscosity and shifted the gelation point to earlier time points. IP6 was further proven to act as a retarder for the cement setting reaction, whereas the effect was stronger for higher IP6 concentrations. Additionally, IP6 favoured the formation of monetite instead of brushite and a better mechanical performance compared to the IP6 free reference cement.


FAU Authors / FAU Editors

Götz-Neunhoeffer, Friedlinde Prof. Dr.
Lehrstuhl für Mineralogie
Hurle, Katrin Dr.
Lehrstuhl für Mineralogie


External institutions with authors

Julius-Maximilians-Universität Würzburg


How to cite

APA:
Hurle, K., Weichhold, J., Brueckner, M., Gbureck, U., Brueckner, T., & Götz-Neunhoeffer, F. (2018). Hydration mechanism of a calcium phosphate cement modified with phytic acid. Acta Biomaterialia, 80, 378-389. https://dx.doi.org/10.1016/j.actbio.2018.09.002

MLA:
Hurle, Katrin, et al. "Hydration mechanism of a calcium phosphate cement modified with phytic acid." Acta Biomaterialia 80 (2018): 378-389.

BibTeX: 

Last updated on 2019-20-07 at 07:17

Share link