Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia

Beitrag in einer Fachzeitschrift

Details zur Publikation

Autorinnen und Autoren: Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Van Kan GA, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, De Meynard C, Donini L, Harris T, Kannt A, Guibert FK, Onder G, Papanicolaou D, Rolland Y, Rooks D, Sieber C, Souhami E, Verlaan S, Zamboni M
Zeitschrift: Journal of the American Medical Directors Association
Jahr der Veröffentlichung: 2011
Band: 12
Heftnummer: 4
Seitenbereich: 249-256
ISSN: 1525-8610


Sarcopenia, the age-associated loss of skeletal muscle mass and function, has considerable societal consequences for the development of frailty, disability, and health care planning. A group of geriatricians and scientists from academia and industry met in Rome, Italy, on November 18, 2009, to arrive at a consensus definition of sarcopenia. The current consensus definition was approved unanimously by the meeting participants and is as follows: Sarcopenia is defined as the age-associated loss of skeletal muscle mass and function. The causes of sarcopenia are multifactorial and can include disuse, altered endocrine function, chronic diseases, inflammation, insulin resistance, and nutritional deficiencies. Although cachexia may be a component of sarcopenia, the 2 conditions are not the same. The diagnosis of sarcopenia should be considered in all older patients who present with observed declines in physical function, strength, or overall health. Sarcopenia should specifically be considered in patients who are bedridden, cannot independently rise from a chair, or who have a measured gait speed less that 1 m/s(-1). Patients who meet these criteria should further undergo body composition assessment using dual energy x-ray absorptiometry with sarcopenia being defined using currently validated definitions. A diagnosis of sarcopenia is consistent with a gait speed of less than 1 m.s(-1) and an objectively measured low muscle mass (eg, appendicular mass relative to ht(2) that is <= 7.23 kg/m(2) in men and <= 5.67 kg/m(2) in women). Sarcopenia is a highly prevalent condition in older persons that leads to disability, hospitalization, and death. (J Am Med Dir Assoc 2011; 12: 249-256)

FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Bauer, Jürgen PD Dr.
Lehrstuhl für Psychogerontologie
Sieber, Cornel Prof. Dr.
Lehrstuhl für Innere Medizin (Geriatrie)

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Zuletzt aktualisiert 2018-14-11 um 09:23