Polypharmacy in the elderly from the clinical toxicologist perspective

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autorinnen und Autoren: Heppner HJ, Christ M, Gosch M, Mühlberg W, Bahrmann P, Bertsch T, Sieber C, Singler K
Zeitschrift: Zeitschrift für Gerontologie und Geriatrie
Verlag: SPRINGER HEIDELBERG
Jahr der Veröffentlichung: 2012
Band: 45
Heftnummer: 6
Seitenbereich: 473-478
ISSN: 0948-6704


Abstract

Polypharmacy is closely associated with multimorbidity in the elderly and can lead to problems and drug interactions.This study assessed polypharmacy in the elderly, tracking inquiries to the Poison Information Centre Nuremberg (PICN) and patients needing toxicological intensive care therapy.From 2006-2009, all PICN inquiries involving individuals > 70 years were tracked, as were cases at the Toxicological Intensive Care Unit (T-ICU) regarding adverse drug reactions (ADRs) and drug poisoning.Of 11,683 PICN calls about pharmaceuticals, 175 (1.5%) were from people > 70 years; 156 (4.8%) of 3,272 T-ICU patients were > 70 years. Calls about psychopharmaceuticals (46.9%) and analgesics (25.7%) were most frequent. Among the T-ICU patients, psychopharmaceuticals like sedatives and hypnotics were frequently involved (20.5%), as were tricyclic antidepressants (17.9%) and analgesics (29.5%). Ethanol was co-ingested by 18.3%.Population-specific poison prevention strategies are needed to reduce toxic exposures. Such strategies could include pharmacist intervention, improved prescriber communication and education regarding the geriatric population, and computerized drug databases.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Bahrmann, Philipp PD Dr.
Lehrstuhl für Innere Medizin (Geriatrie)
Mühlberg, Wolfgang PD Dr.
Medizinische Fakultät
Sieber, Cornel Prof. Dr.
Lehrstuhl für Innere Medizin (Geriatrie)
Singler, Katrin Prof. Dr.
Lehrstuhl für Innere Medizin (Geriatrie)


Einrichtungen weiterer Autorinnen und Autoren

Klinikum Nürnberg


Zitierweisen

APA:
Heppner, H.J., Christ, M., Gosch, M., Mühlberg, W., Bahrmann, P., Bertsch, T.,... Singler, K. (2012). Polypharmacy in the elderly from the clinical toxicologist perspective. Zeitschrift für Gerontologie und Geriatrie, 45(6), 473-478. https://dx.doi.org/10.1007/s00391-012-0383-6

MLA:
Heppner, H. J., et al. "Polypharmacy in the elderly from the clinical toxicologist perspective." Zeitschrift für Gerontologie und Geriatrie 45.6 (2012): 473-478.

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