Significance of frailty for predicting adverse clinical outcomes in different patient groups with specific medical conditions

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autorinnen und Autoren: Ritt M, Gassmann KG, Sieber C
Zeitschrift: Zeitschrift für Gerontologie und Geriatrie
Verlag: SPRINGER HEIDELBERG
Jahr der Veröffentlichung: 2016
Band: 49
Heftnummer: 7
Seitenbereich: 567-572
ISSN: 0948-6704


Abstract

Frailty is a major health burden in an aging society. It constitutes a clinical state of reduced physiological reserves that is associated with a diminished ability to withstand internal and external stressors. Frail patients have an increased risk for adverse clinical outcomes, such as mortality, readmission to hospital, institutionalization and falls. Of further clinical interest, frailty might be at least in part reversible in some patients and subject to preventive strategies. In daily clinical practice older patients with a complex health status, who are mostly frail or at least at risk of developing frailty, are frequently cared for by geriatricians. Recently, clinicians and scientists from other medical disciplines, such as cardiology, pulmonology, gastroenterology, nephrology, endocrinology, rheumatology, surgery and critical care medicine also discovered frailty to be an interesting instrument for risk stratification of patients, including younger patients. In this review we highlight the results of recent studies that demonstrated the significance of frailty to predict adverse clinical outcomes in patients with specific medical conditions, such as cardiac, lung, liver and kidney diseases as well as diabetes mellitus, osteoarthritis, trauma patients, patients undergoing surgery and critically ill patients. Multiple studies in patients with the aforementioned specific medical conditions could be identified demonstrating a predictive role of frailty for several adverse clinical outcomes. The association between frailty and adverse clinical outcomes reported in these studies was in part independent of several major potential confounder factors, such as age, sex, race, comorbidities and disabilities and were also detected in younger patients.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Sieber, Cornel Prof. Dr.
Lehrstuhl für Innere Medizin (Geriatrie)


Einrichtungen weiterer Autorinnen und Autoren

Waldkrankenhaus St Marien


Zitierweisen

APA:
Ritt, M., Gassmann, K.-G., & Sieber, C. (2016). Significance of frailty for predicting adverse clinical outcomes in different patient groups with specific medical conditions. Zeitschrift für Gerontologie und Geriatrie, 49(7), 567-572. https://dx.doi.org/10.1007/s00391-016-1128-8

MLA:
Ritt, Martin, Karl-Guenter Gassmann, and Cornel Sieber. "Significance of frailty for predicting adverse clinical outcomes in different patient groups with specific medical conditions." Zeitschrift für Gerontologie und Geriatrie 49.7 (2016): 567-572.

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Zuletzt aktualisiert 2018-07-11 um 21:08