Comparing the predictive accuracy of frailty, comorbidity, and disability for mortality: a 1-year follow-up in patients hospitalized in geriatric wards

Ritt M, Ritt JI, Sieber C, Gaßmann KG (2017)


Publication Status: Published

Publication Type: Journal article

Publication year: 2017

Journal

Publisher: DOVE MEDICAL PRESS LTD

Book Volume: 12

Pages Range: 293-304

DOI: 10.2147/CIA.S124342

Abstract

Background: Studies evaluating and comparing the power of frailty, comorbidity, and disability instruments, together and in parallel, for predicting mortality are limited.Objective: This study aimed to evaluate and compare the measures of frailty, comorbidity, and disability in predicting 1-year mortality in geriatric inpatients.Design: Prospective cohort study.Patients and setting: A total of 307 inpatients aged >= 65 years in geriatric wards of a general hospital participated in the study.Measurements: The patients were evaluated in relation to different frailty, comorbidity, and disability instruments during their hospital stays. These included three frailty (the seven-category Clinical Frailty Scale [CFS-7], a 41-item frailty index [FI], and the FRAIL scale), two comorbidity (the Cumulative Illness Rating Scale for Geriatrics [CIRS-G] and the comorbidity domain of the FI [Comorbidity-D-FI]), and two disability instruments (disability in basic activities of daily living [ADL-Katz] and the instrumental and basic activities of daily living domains of the FI [IADL/ADL-D-FI]). The patients were followed-up over 1 year.Results: Using FI, CIRS-G, Comorbidity-D-FI, and ADL-Katz, this study identified a patient group with a high (>= 50%) 1-year mortality rate in all of the patients and the two patient subgroups (ie, patients aged 65-82 years and >= 83 years). The CFS-7, FI, FRAIL scale, CIRS-G, Comorbidity-D-FI, and IADL/ADL-D-FI (analyzed as full scales) revealed useful discriminative accuracy for 1-year mortality (ie, an area under the curve >0.7) in all the patients and the two patient subgroups (all P<0.001). Thereby, CFS-7 (in all patients and the two patient subgroups) and FI (in the subgroup of patients aged >= 83 years) showed greater discriminative accuracy for 1-year mortality compared to other instruments (all P<0.05).Conclusion: All the different instruments emerged as suitable tools for risk stratification in geriatric inpatients. Among them, CFS-7, and in those patients aged >= 83 years, also the FI, might most accurately predict 1-year mortality in the aforementioned group of individuals.

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APA:

Ritt, M., Ritt, J.I., Sieber, C., & Gaßmann, K.-G. (2017). Comparing the predictive accuracy of frailty, comorbidity, and disability for mortality: a 1-year follow-up in patients hospitalized in geriatric wards. Clinical Interventions in Aging, 12, 293-304. https://doi.org/10.2147/CIA.S124342

MLA:

Ritt, Martin, et al. "Comparing the predictive accuracy of frailty, comorbidity, and disability for mortality: a 1-year follow-up in patients hospitalized in geriatric wards." Clinical Interventions in Aging 12 (2017): 293-304.

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