Parallel Variable Interscan Time Analysis (VISTA) OCTA and en Face Doppler OCT of Optic Disc and Peripapillary Vasculature

Lee B, Moult EM, Ploner S, Alibhai AY, Rebhun CB, Moreira-Neto C, Husvogt L, Maier A, Wollstein G, Schuman J, Waheed NK, Duker JS, Fujimoto JG (2017)

Publication Language: English

Publication Type: Conference contribution, Abstract of lecture

Publication year: 2017

Book Volume: 58

Pages Range: tbd

Edition: 8

Conference Proceedings Title: Investigative Ophthalmology & Visual Science

Event location: Baltimore, MD, USA US

URI: https://www5.informatik.uni-erlangen.de/Forschung/Publikationen/2017/Lee17-PVI.pdf

Abstract

Purpose : The introduction of optical coherence tomography angiography (OCTA) allows clinicians to study the microvascular alterations that occur in diabetic retinopathy (DR). Standard OCTA systems yield a detailed picture of the presence of vasculature, but have limited dynamic range and provide little information about blood flow speeds. Our group has recently developed variable interscan time analysis (VISTA), which provides a framework for studying relative blood flow speeds using OCTA. This study investigates VISTA to assess microvascular blood flow speeds in eyes with DR.

Methods : Using a VISTA protocol we analyzed 3 eyes with mild non-proliferative DR (NPDR) (2 patients; 66.7±2.31 y/o), 5 eyes with moderate NPDR (3 patients; 57.6±16.58 y/o), 5 eyes with severe NPDR (4 patients; 51.8±13.44 y/o), and 8 eyes with proliferative DR (PDR) (6 patients; 57.0±13.38 y/o).

Results : We observed a range of flow distributions associated with capillary looping/microaneurysms, tortuous vessels, dilated vessels, and neovasculature vessels. Representative VISTA-OCTA images are shown in Figures 1 and 2.

Conclusions : VISTA is a useful framework for studying blood flow speeds in eyes with DR.

Authors with CRIS profile

Stefan Ploner Lehrstuhl für Informatik 5 (Mustererkennung) Lennart Husvogt Lehrstuhl für Informatik 5 (Mustererkennung) Andreas Maier Lehrstuhl für Informatik 5 (Mustererkennung)

Involved external institutions

Tufts Medical Center US United States (USA) (US) Tufts University US United States (USA) (US) Massachusetts Institute of Technology (MIT) US United States (USA) (US) University of Pittsburgh Medical Center (UPMC) US United States (USA) (US)

How to cite

APA:

Lee, B., Moult, E.M., Ploner, S., Alibhai, A.Y., Rebhun, C.B., Moreira-Neto, C.,... Fujimoto, J.G. (2017, June). Parallel Variable Interscan Time Analysis (VISTA) OCTA and en Face Doppler OCT of Optic Disc and Peripapillary Vasculature. Paper presentation at ARVO Annual Meeting 2017, Baltimore, MD, USA, US.

MLA:

Lee, Byungkun, et al. "Parallel Variable Interscan Time Analysis (VISTA) OCTA and en Face Doppler OCT of Optic Disc and Peripapillary Vasculature." Presented at ARVO Annual Meeting 2017, Baltimore, MD, USA 2017.

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