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SlicerOCT: A 3-D visualization platform for orthoplane viewing of OCT(A) datasets

Husvogt L, Moult EM, Lee B, Waheed NK, Hornegger J, Spaide RF, Maier A, Fujimoto JG (2016)

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Publication Language: English

Publication Type: Conference contribution

Publication year: 2016

Publisher: ARVO

City/Town: ARVO

Book Volume: 57

Pages Range: 5974

Edition: 12

Conference Proceedings Title: Investigative Ophthalmology & Visual Science

Event location: Seattle, WA, USA

URI: https://www5.informatik.uni-erlangen.de/Forschung/Publikationen/2016/Husvogt16-SA3.pdf

Abstract

Purpose : 3D Slicer is a visualization platform for radiographic data (computed tomography, magnetic resonance imaging, ultrasound). The purpose of this study is to extend 3D Slicer to enable simultaneous, orthoplane viewing of volumetric optical coherence tomography (OCT) and OCT angiography (OCTA) data.

Methods : We propose an OCT specific module, “SlicerOCT,” which leverages 3D Slicer’s existing capabilities for orthoplane viewing and volume rendering. OCT and OCTA data are stored in different layers, which allows simultaneous display; layers can be toggled on and off. OCT specific functions, such as volume projection and OCTA thresholding, are available. Orthoplane views can be scrolled through in a manner analogous to a conventional radiology viewer and data can be rendered volumetrically.

Results : Figure 1 shows a SlicerOCT display of OCT and OCTA data from a patient with exudative age-related macular degeneration (AMD). The choroidal neovascularization (CNV) is clearly visible in the OCT angiograms and corresponding structural en face displays (right panels), while CNV location under the retinal pigment epithelium (RPE) and intraretinal cysts are visible in the OCT B-scan display (bottom left). Figure 2 shows a SlicerOCT display of OCT and OCTA data from a patient with geographic atrophy (GA). Areas of RPE alteration are visible on OCTA, while areas of choriocapillaris loss are seen on OCTA. Unlike traditional en face visualization of OCTA data, orthoplane viewing enables interpretation of individual OCTA B-scans, which can help identify artifacts, such as incorrect segmentation, signal attenuation, and decorrelation tails.

Conclusions : SlicerOCT enables simultaneous, orthoplane visualization of OCT and OCTA datasets, which promises to enable more accurate interpretation of OCTA data and is especially crucial for studying diseases whose progression alters both structure and blood flow.

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How to cite

APA:

Husvogt, L., Moult, E.M., Lee, B., Waheed, N.K., Hornegger, J., Spaide, R.F.,... Fujimoto, J.G. (2016). SlicerOCT: A 3-D visualization platform for orthoplane viewing of OCT(A) datasets. In Investigative Ophthalmology & Visual Science (pp. 5974). Seattle, WA, USA, US: ARVO: ARVO.

MLA:

Husvogt, Lennart, et al. "SlicerOCT: A 3-D visualization platform for orthoplane viewing of OCT(A) datasets." Proceedings of the ARVO Annual Meeting 2016, Seattle, WA, USA ARVO: ARVO, 2016. 5974.

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