Synthesis and characterization of manganese containing mesoporous bioactive glass nanoparticles for biomedical applications

Nawaz Q, Ur Rehman MA, Burkovski A, Schmidt J, Shahid A, Peukert W, Boccaccini AR (2018)

Publication Type: Journal article, Original article

Publication year: 2018

Journal

Journal of Materials Science: Materials in Medicine Springer

URI: https://link.springer.com/article/10.1007/s10856-018-6070-4

Abstract

Mesoporous bioactive glass (BG) nanoparticles based in the system: SiO2–P2O5-CaO-MnO were synthesized via a modified Stöber process at various concentrations of Mn (0-7 mol%). The synthesized manganese-doped BG nanoparticles were characterized in terms of morphology, composition, in vitro bioactivity and antibacterial activity. Scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Brunauer-Emmett-Teller (BET) analysis confirmed that the particles had spherical morphology (mean particle size: 110 nm) with disordered mesoporous structure. Energy dispersive X-ray spectroscopy (EDX) confirmed the presence of Mn, Ca, Si and P in the synthesized Mn-doped BG particles. Moreover, X-ray diffraction (XRD) analysis has shown that Mn has been incorporated into the amorphous silica network (bioactive glass). More over, it was found that manganese-doped BG particles form apatite crystals upon being immersed in simulated body fluid (SBF). Inductively coupled plasma atomic emission spectroscopy (ICP-OES) measurements confirmed that Mn is released in a sustained mannerBacillus subtilis , Pseudomonas aeruginosaaeruginosa Staphylococcus aureus . The multifunctional BG nanoparticles for bone tissue engineering. The results indicate that the incorporation of Mn into the bioactive glass network is effective. and

Authors with CRIS profile

Qaisar Nawaz Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Muhammad Atiq Ur Rehman Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Andreas Burkovski Professur für Mikrobiologie Jochen Schmidt Lehrstuhl für Partikelsynthese (LFG) Ameen Shahid Lehrstuhl für Chemische Reaktionstechnik (CRT) Wolfgang Peukert Lehrstuhl für Partikelsynthese (LFG) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

How to cite

APA:

Nawaz, Q., Ur Rehman, M.A., Burkovski, A., Schmidt, J., Shahid, A., Peukert, W., & Boccaccini, A.R. (2018). Synthesis and characterization of manganese containing mesoporous bioactive glass nanoparticles for biomedical applications. Journal of Materials Science: Materials in Medicine. https://doi.org/10.1007/s10856-018-6070-4

MLA:

Nawaz, Qaisar, et al. "Synthesis and characterization of manganese containing mesoporous bioactive glass nanoparticles for biomedical applications." Journal of Materials Science: Materials in Medicine (2018).

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