CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication

Journal article


Publication Details

Author(s): Dettmer J, Ursache R, Campilho A, Miyashima S, Belevich I, O'Regan S, Mullendore DL, Yadav SR, Lanz C, Beverina L, Papagni A, Schneeberger K, Weigel D, Stierhof YD, Moritz T, Knoblauch M, Jokitalo E, Helariutta Y
Journal: Nature Communications
Publisher: Nature Publishing Group: Nature Communications
Publication year: 2014
Volume: 5
ISSN: 2041-1723


Abstract


Phloem, a plant tissue responsible for long-distance molecular transport, harbours specific junctions, sieve areas, between the conducting cells. To date, little is known about the molecular framework related to the biogenesis of these sieve areas. Here we identify mutations at the CHER1/AtCTL1 locus of Arabidopsis thaliana. The mutations cause several phenotypic abnormalities, including reduced pore density and altered pore structure in the sieve areas associated with impaired phloem function. CHER1 encodes a member of a poorly characterized choline transporter-like protein family in plants and animals. We show that CHER1 facilitates choline transport, localizes to the trans-Golgi network, and during cytokinesis is associated with the phragmoplast. Consistent with its function in the elaboration of the sieve areas, CHER1 has a sustained, polar localization in the forming sieve plates. Our results indicate that the regulation of choline levels is crucial for phloem development and conductivity in plants.



FAU Authors / FAU Editors

Dettmer, Jan Dr.
Lehrstuhl für Zellbiologie


External institutions
Eberhard Karls Universität Tübingen
Helsingin yliopisto / University of Helsinki
Max-Planck-Institut für Entwicklungsbiologie / Max Planck Institute for Developmental Biology
Max-Planck-Institut für Pflanzenzüchtungsforschung / Max Planck Institute for Plant Breeding Research
Swedish University of Agricultural Sciences / Sveriges Lantbruksuniversitet (SLU)
Universidade do Porto
University of Milano-Bicocca / Università degli Studi di Milano-Bicocca, UNIMIB
University of Paris 5 - René Descartes / Université Paris V René Descartes
Washington State University (WSU)


How to cite

APA:
Dettmer, J., Ursache, R., Campilho, A., Miyashima, S., Belevich, I., O'Regan, S.,... Helariutta, Y. (2014). CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication. Nature Communications, 5. https://dx.doi.org/10.1038/ncomms5276

MLA:
Dettmer, Jan, et al. "CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication." Nature Communications 5 (2014).

BibTeX: 

Last updated on 2018-20-07 at 23:23