Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autor(en): Östreicher C, Bartenbacher S, Pischetsrieder M
Zeitschrift: Journal of Proteomics
Verlag: ELSEVIER SCIENCE BV
Jahr der Veröffentlichung: 2017
Band: 166
Seitenbereich: 27-38
ISSN: 1874-3919


Abstract


The present study demonstrated that the major components of cinnamon and rosemary, respectively, i.e. cinnamaldehyde and carnosol, are potent alimentary candidates to increase the expression of cytoprotective enzymes in the human colon. Among the investigated enzymes, NAD(P)H dehydrogenase [quinone] 1 (NQO1) was most susceptible towards modulation by phytochemicals. NQ01 exerts its cytoprotective activity by detoxifying electrophilic and oxidative xenobiotics with quinone structure. (C) 2017 Elsevier B.V. All rights reserved.



FAU-Autoren / FAU-Herausgeber

Bartenbacher, Sven
Lehrstuhl für Lebensmittelchemie (Henriette-Schmidt-Burkhardt Lehrstuhl)
Östreicher, Christiane
Lehrstuhl für Lebensmittelchemie (Henriette-Schmidt-Burkhardt Lehrstuhl)
Pischetsrieder, Monika Prof. Dr.
Lehrstuhl für Lebensmittelchemie (Henriette-Schmidt-Burkhardt Lehrstuhl)


Zusätzliche Organisationseinheit(en)
Emil-Fischer-Zentrum (Emil Fischer Center)


Zitierweisen

APA:
Östreicher, C., Bartenbacher, S., & Pischetsrieder, M. (2017). Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells. Journal of Proteomics, 166, 27-38. https://dx.doi.org/10.1016/j.jprot.2017.06.023

MLA:
Östreicher, Christiane, Sven Bartenbacher, and Monika Pischetsrieder. "Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells." Journal of Proteomics 166 (2017): 27-38.

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Zuletzt aktualisiert 2018-19-07 um 19:23