Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells

Östreicher C, Bartenbacher S, Pischetsrieder M (2017)


Publication Status: Published

Publication Type: Journal article

Publication year: 2017

Journal

Publisher: ELSEVIER SCIENCE BV

Book Volume: 166

Pages Range: 27-38

DOI: 10.1016/j.jprot.2017.06.023

Abstract

The present study demonstrated that the major components of cinnamon and rosemary, respectively, i.e. cinnamaldehyde and carnosol, are potent alimentary candidates to increase the expression of cytoprotective enzymes in the human colon. Among the investigated enzymes, NAD(P)H dehydrogenase [quinone] 1 (NQO1) was most susceptible towards modulation by phytochemicals. NQ01 exerts its cytoprotective activity by detoxifying electrophilic and oxidative xenobiotics with quinone structure. (C) 2017 Elsevier B.V. All rights reserved.

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APA:

Östreicher, C., Bartenbacher, S., & Pischetsrieder, M. (2017). Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells. Journal of Proteomics, 166, 27-38. https://dx.doi.org/10.1016/j.jprot.2017.06.023

MLA:

Östreicher, Christiane, Sven Bartenbacher, and Monika Pischetsrieder. "Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells." Journal of Proteomics 166 (2017): 27-38.

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