Phantom Studies of Neutron Capture of Boron Containing Magnetic Nanoparticles

Tietze R, Dürr S, Lyer S, Taccardi N, Wasserscheid P, Canella L, Wagner FM, Petry W, Alexiou C (2013)

Publication Type: Journal article

Publication year: 2013

Journal

Biomedizinische Technik Walter de Gruyter

DOI: 10.1515/bmt-2013-4045

Abstract

The main burden that hinders the translation of neutron capture therapy drafts to human trials is the difficulty to deposit a sufficient amount of boron in the targeted tumour areas. Magnetic nanoparticles containing B-10 isotopes attempt to be enriched in tumour tissues selectively by the means of external magnetic fields to overcome these restrictions. First pilot measurements of the neutron depth penetration investigated the neutron flux density in dependence of depth, presence of boron and additional presence of iron oxide nanoparticles. These irradiation experiments on different phantoms evidenced no disturbing attenuation effects of the applied boron and the co-present nanoparticles in the samples.

Authors with CRIS profile

Rainer Tietze Department of Otorhinolaryngology – Head and Neck Surgery Stefan Lyer Department of Otorhinolaryngology – Head and Neck Surgery Nicola Taccardi Lehrstuhl für Chemische Reaktionstechnik Peter Wasserscheid Lehrstuhl für Chemische Reaktionstechnik Christoph Alexiou Professur für Nanomedizin

Additional Organisation(s)

Exzellenz-Cluster Engineering of Advanced Materials

Involved external institutions

Technische Universität München (TUM)

Germany (DE)

How to cite

APA:

Tietze, R., Dürr, S., Lyer, S., Taccardi, N., Wasserscheid, P., Canella, L.,... Alexiou, C. (2013). Phantom Studies of Neutron Capture of Boron Containing Magnetic Nanoparticles. Biomedizinische Technik. https://dx.doi.org/10.1515/bmt-2013-4045

MLA:

Tietze, Rainer, et al. "Phantom Studies of Neutron Capture of Boron Containing Magnetic Nanoparticles." Biomedizinische Technik (2013).

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