Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS)

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autorinnen und Autoren: Cruz-Jentoft AJ, Landi F, Schneider SM, Zuniga C, Arai H, Boirie Y, Chen LK, Fielding RA, Martin FC, Michel JP, Sieber C, Stout JR, Studenski SA, Vellas B, Woo J, Zamboni M, Cederholm T
Zeitschrift: Age and ageing
Jahr der Veröffentlichung: 2014
Band: 43
Heftnummer: 6
Seitenbereich: 748-59
ISSN: 0002-0729


Abstract

to examine the clinical evidence reporting the prevalence of sarcopenia and the effect of nutrition and exercise interventions from studies using the consensus definition of sarcopenia proposed by the European Working Group on Sarcopenia in Older People (EWGSOP).PubMed and Dialog databases were searched (January 2000-October 2013) using pre-defined search terms. Prevalence studies and intervention studies investigating muscle mass plus strength or function outcome measures using the EWGSOP definition of sarcopenia, in well-defined populations of adults aged >=50 years were selected.prevalence of sarcopenia was, with regional and age-related variations, 1-29% in community-dwelling populations, 14-33% in long-term care populations and 10% in the only acute hospital-care population examined. Moderate quality evidence suggests that exercise interventions improve muscle strength and physical performance. The results of nutrition interventions are equivocal due to the low number of studies and heterogeneous study design. Essential amino acid (EAA) supplements, including ~2.5 g of leucine, and ?-hydroxy ?-methylbutyric acid (HMB) supplements, show some effects in improving muscle mass and function parameters. Protein supplements have not shown consistent benefits on muscle mass and function.prevalence of sarcopenia is substantial in most geriatric settings. Well-designed, standardised studies evaluating exercise or nutrition interventions are needed before treatment guidelines can be developed. Physicians should screen for sarcopenia in both community and geriatric settings, with diagnosis based on muscle mass and function. Supervised resistance exercise is recommended for individuals with sarcopenia. EAA (with leucine) and HMB may improve muscle outcomes.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Sieber, Cornel Prof. Dr.
Lehrstuhl für Innere Medizin (Geriatrie)


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Catholic University of the Sacred Heart / Università Cattolica del Sacro Cuore
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Geneva University Hospitals / Hôpitaux universitaires de Genève (HUG)
Guy's and St Thomas'
Hospital Universitario Ramón y Cajal
Kyoto University / 京都大学 Kyōto daigaku
L’université Blaise Pascal (L'UBP) / Blaise Pascal University
Taipei Veterans General Hospital / 台北榮民總醫院
The Chinese University of Hong Kong (CUHK)
Tufts University
Université Nice Sophia Antipolis / University of Nice Sophia Antipolis
University of Central Florida (UCF)
University of Pittsburgh
University of Verona / Università degli Studi di Verona
Uppsala University


Zitierweisen

APA:
Cruz-Jentoft, A.J., Landi, F., Schneider, S.M., Zuniga, C., Arai, H., Boirie, Y.,... Cederholm, T. (2014). Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age and ageing, 43(6), 748-59. https://dx.doi.org/10.1093/ageing/afu115

MLA:
Cruz-Jentoft, Alfonso J., et al. "Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS)." Age and ageing 43.6 (2014): 748-59.

BibTeX: 

Zuletzt aktualisiert 2018-10-10 um 02:21