Flagellates as model system for gravity detection of single cells

Conference contribution
(Conference Contribution)


Publication Details

Author(s): Lebert M, Richter P, Daiker V, Schuster M, Tebart J, Strauch S, Häder DP
Publication year: 2010


Abstract


Euglena gracilis is a unicellular, photosynthetic organism which uses light and gravity as en-vironmental hints to reach and stay in horizons of the water column which are optimal for growth and reproduction. The orientation in respect to light (so called positive and nega-tive phototaxis, i.e. movement toward or away of a light source) was well known and fairly good understood. In contrast, knowledge about the movement away from the centre of gravity (negative gravitaxis) was rather scarce. Over a century it was unclear whether orientation in respect to the gravity vector is based on a physical or a physiological mechanism. Recent results clearly favour the latter. Knock-down mutants (RNAi) were characterized which define certain key components of the gravitactic signal transduction chain. These key components include a TRP-like channel, a gravitaxis-specific calmodulin and a protein kinase A. The molecular characterization of these components is currently performed and will be presented. Euglena is not only a model system for the close understanding of gravity detection in single cells, but can also be used as photosynthetic component, i.e. oxygen source and carbon dioxide as well as nitrogenic components sink in Closed Environmental Systems (CES). Due CES are systems of choice in times of scarce flight opportunities. They allow a massive sample sharing and combine possibilities to do microgravity research for biologists but also for engineers, physicists and material scientists. Recent attempts include Aquacells and Omegahab. In the near future miniaturized systems (Chinese ShenZhou) as well as advanced CES will be flown or tested, respectively. Current attempts and plans will be presented.



FAU Authors / FAU Editors

Daiker, Viktor Dr.
Lehrstuhl für Zellbiologie
Häder, Donat-Peter Prof. Dr.
Naturwissenschaftliche Fakultät
Lebert, Michael PD Dr.
Lehrstuhl für Zellbiologie
Richter, Peter Dr.
Lehrstuhl für Zellbiologie
Schuster, Martin
Lehrstuhl für Zellbiologie
Strauch, Sebastian Dr.
Lehrstuhl für Zellbiologie


How to cite

APA:
Lebert, M., Richter, P., Daiker, V., Schuster, M., Tebart, J., Strauch, S., & Häder, D.-P. (2010). Flagellates as model system for gravity detection of single cells. Bremen, DE.

MLA:
Lebert, Michael, et al. "Flagellates as model system for gravity detection of single cells." Proceedings of the 38th COSPAR Scientific Assembly, Bremen 2010.

BibTeX: 

Last updated on 2018-08-08 at 05:13