Boron containing magnetic nanoparticles for neutron capture therapy - an innovative approach for specifically targeting tumors

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autor(en): Tietze R, Unterweger H, Dürr S, Lyer S, Canella L, Kudejova P, Wagner FM, Petry W, Taccardi N, Alexiou C
Zeitschrift: Applied Radiation and Isotopes
Verlag: Elsevier
Jahr der Veröffentlichung: 2015
Band: 106
Seitenbereich: 151-5
ISSN: 0969-8043


Abstract

The selective delivery of (10)B into the tumor tissue remains to be further improved for successful and reliable Boron Neutron Capture Therapy applications. Magnetic Drug Targeting using intraarterially administered superparamagnetic nanoparticles and external magnetic fields already exhibited convincing results in terms of highly efficient and selective drug deposition. Using the same technique for the targeted (10)B delivery is a promising new approach. Here, systematic irradiation experiments of phantom cubes containing different concentrations of boron and nanoparticles as well as varying three-dimensional arrangements have been performed.


FAU-Autoren / FAU-Herausgeber

Alexiou, Christoph Prof. Dr.
Professur für Nanomedizin
Taccardi, Nicola Dr.
Lehrstuhl für Chemische Reaktionstechnik
Unterweger, Harald Dr.-Ing.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie


Autor(en) der externen Einrichtung(en)
Technische Universität München (TUM)


Zitierweisen

APA:
Tietze, R., Unterweger, H., Dürr, S., Lyer, S., Canella, L., Kudejova, P.,... Alexiou, C. (2015). Boron containing magnetic nanoparticles for neutron capture therapy - an innovative approach for specifically targeting tumors. Applied Radiation and Isotopes, 106, 151-5. https://dx.doi.org/10.1016/j.apradiso.2015.07.028

MLA:
Tietze, Rainer, et al. "Boron containing magnetic nanoparticles for neutron capture therapy - an innovative approach for specifically targeting tumors." Applied Radiation and Isotopes 106 (2015): 151-5.

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Zuletzt aktualisiert 2018-09-10 um 07:17