Natural Cuban zeolites for medical use and their histamine binding capacity

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autor(en): Selvam T, Schwieger W, Dathe W
Zeitschrift: Clay Minerals
Verlag: Mineralogical Society
Jahr der Veröffentlichung: 2014
Band: 49
Seitenbereich: 501-512
ISSN: 0009-8558


Abstract


The work reported herein involves the characterization of natural zeolites from two different mines (San Andres and Tasajeras; Cuba) using XRD, SEM, TG-DTA, ICP and surface area measurements. In addition, the chemical composition of zeolites, the heavy metal and environmental organic toxins content, the ion exchange rates, stability under biological conditions using simulated body fluids as well as the binding capacity for histamine have been investigated with a view to using them as medical products. The investigated zeolites contain clinoptilolite and mordenite as major phases. Furthermore, the samples are apparently free from fibrous materials according to SEM observations. In particular, the San Andres zeolite binds remarkable amounts of histamine which are nearly irreversible under acidic (pH = 1; 12.4 mg/g) and neutral conditions (pH = 7; 15.7 mg/g), respectively. Thus, the San Andres sample may well be applied as a medical product due to its excellent binding capacity for histamine along with its remaining optimum physico-chemical characteristics.



FAU-Autoren / FAU-Herausgeber

Schwieger, Wilhelm Prof. Dr.
Professur für Technische Chemie (Reaktionstechnik)


Autor(en) der externen Einrichtung(en)
Heck Bio-Pharma GmbH


Zitierweisen

APA:
Selvam, T., Schwieger, W., & Dathe, W. (2014). Natural Cuban zeolites for medical use and their histamine binding capacity. Clay Minerals, 49, 501-512. https://dx.doi.org/10.1180/claymin.2014.049.4.01

MLA:
Selvam, Thangaraj, Wilhelm Schwieger, and W. Dathe. "Natural Cuban zeolites for medical use and their histamine binding capacity." Clay Minerals 49 (2014): 501-512.

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Zuletzt aktualisiert 2018-05-07 um 03:23