Natural Cuban zeolites for medical use and their histamine binding capacity

Beitrag in einer Fachzeitschrift

Details zur Publikation

Autorinnen und Autoren: Selvam T, Schwieger W, Dathe W
Zeitschrift: Clay Minerals
Verlag: Mineralogical Society
Jahr der Veröffentlichung: 2014
Band: 49
Seitenbereich: 501-512
ISSN: 0009-8558


The work reported herein involves the characterization of natural zeolites from two different mines (San Andres and Tasajeras; Cuba) using XRD, SEM, TG-DTA, ICP and surface area measurements. In addition, the chemical composition of zeolites, the heavy metal and environmental organic toxins content, the ion exchange rates, stability under biological conditions using simulated body fluids as well as the binding capacity for histamine have been investigated with a view to using them as medical products. The investigated zeolites contain clinoptilolite and mordenite as major phases. Furthermore, the samples are apparently free from fibrous materials according to SEM observations. In particular, the San Andres zeolite binds remarkable amounts of histamine which are nearly irreversible under acidic (pH = 1; 12.4 mg/g) and neutral conditions (pH = 7; 15.7 mg/g), respectively. Thus, the San Andres sample may well be applied as a medical product due to its excellent binding capacity for histamine along with its remaining optimum physico-chemical characteristics.

FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Schwieger, Wilhelm Prof. Dr.
Professur für Technische Chemie (Reaktionstechnik)

Einrichtungen weiterer Autorinnen und Autoren

Heck Bio-Pharma GmbH


Selvam, T., Schwieger, W., & Dathe, W. (2014). Natural Cuban zeolites for medical use and their histamine binding capacity. Clay Minerals, 49, 501-512.

Selvam, Thangaraj, Wilhelm Schwieger, and W. Dathe. "Natural Cuban zeolites for medical use and their histamine binding capacity." Clay Minerals 49 (2014): 501-512.


Zuletzt aktualisiert 2018-05-07 um 03:23