Combination of olefin metathesis and enzymatic ester hydrolysis in aqueous media in a one-pot synthesis

Tenbrink K, Seßler M, Schatz J, Gröger H (2011)


Publication Type: Journal article, Original article

Publication year: 2011

Journal

Original Authors: Tenbrink K., Seßler M., Schatz J., Groger H.

Publisher: Wiley-VCH Verlag

Book Volume: 353

Pages Range: 2363-2367

Journal Issue: 13

DOI: 10.1002/adsc.201100403

Abstract

A new synthetic method for the preparation of cyclic malonic acid monoesters in aqueous media was developed based on the combination of a metathesis reaction and subsequent biocatalytic hydrolysis with a pig liver esterase in a one-pot synthesis. Both reaction steps proceed smoothly under optimized conditions in aqueous media requiring only a low amount of the metal catalyst for the metathesis reaction. Notably, the applied biocatalyst turned out to be highly compatible with the metal catalyst showing no significant influence on the enzyme activity. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Authors with CRIS profile

How to cite

APA:

Tenbrink, K., Seßler, M., Schatz, J., & Gröger, H. (2011). Combination of olefin metathesis and enzymatic ester hydrolysis in aqueous media in a one-pot synthesis. Advanced Synthesis & Catalysis, 353(13), 2363-2367. https://dx.doi.org/10.1002/adsc.201100403

MLA:

Tenbrink, Katharina, et al. "Combination of olefin metathesis and enzymatic ester hydrolysis in aqueous media in a one-pot synthesis." Advanced Synthesis & Catalysis 353.13 (2011): 2363-2367.

BibTeX: Download